Phlebologie 2011; 40(02): 95-97
DOI: 10.1055/s-0037-1621757
Kasuistik
Schattauer GmbH

Analgesic effect of topical sevoflurane on venous leg ulcer with intractable pain

Schmerzstillende Wirkung von topisch angewandtem Sevofluran auf ein venöses Geschwür mit the-rapieresistenten Schmerzen
M. Gerónimo-Pardo
1   Department of Anesthesiology, Reanimation and Pain Treatment, Complejo Hospitalario Universitario of Albacete
,
A. Martínez-Monsalve
2   Department of Vascular Surgery, Complejo Hospitalario Universitario of Albacete
,
M. Martínez-Serrano
3   Department of Clinical Microbiology and Parasitology, Complejo Hospitalario Universitario of Albacete
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received:18. November 2010

Accepted:20. Januar 2011

Publikationsdatum:
30. Dezember 2017 (online)

Summary

We are presenting the case of a patient with a very painful venous ulcer for whom therapy with different analgesic combinations (including acetaminophen, metamizol, tramadol, morphine, fentanyl, buprenorphine, pregabal-in, gabapentin, as well as applications of lido-caine/prilocaine eutectic cream and infusion of epidural ropivacaine) was unsatisfactory. Analgesic control was finally achieved through applications of liquid sevoflurane to the wound, which resulted in immediate, intense, and long-lasting analgesia. To the patients satisfaction, the same response was obtained throughout the 16 days it took the ulcer to heal. The compassionate use of sevoflurane in this innovative and promising manner warrants further research to evaluate its efficacy and safety.

Zusammenfassung

Wir stellen den Fall eines Patienten mit einem sehr schmerzhaften venösen Geschwür vor, bei welchem die Therapie mit verschiedenen Schmerzmittelkombinationen (einschließlich Paracetamol, Metamizol, Tramadol, Morphin, Fentanyl, Buprenorphin, Pregabalin, Gabapen-tin, sowie der lokalen Anwendung von Lido-cain/Prilocain Creme und epiduralen Infusionen mit Ropivacain) unbefriedigend war. Schmerzstillende Kontrolle wurde schließlich erreicht durch direkte Anwendung von flüssi-gem Sevofluran auf der Wunde, die zur unmittelbaren, intensiven und lang anhaltenden Analgesie führte. Zur Zufriedenheit des Patien-ten wurde eine ähnliche Reaktion während des Zeitraums von 16 Tagen erreicht, in dem das Geschwür heilte. Die direkte/topische Anwen-dung von Sevofluran mit dieser innovativen und vielversprechenden Methode rechtfertigt weitere Untersuchungen zur Bewertung der Wirksamkeit und Sicherheit von Sevofluran.

 
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