¹⁸F-fluorocholine may be taken-up by brown adipose tissue

• References

• 1 Baba S, Engles JM, Huso DL. et al. Comparison of uptake of multiple clinical radiotracers into brown adipose tissue under cold-stimulated and non-stimulated conditions. J Nucl Med 2007; 48: 1715-1723.
• 2 Bartelt A, Bruns OT, Reimer R. et al. Brown adipose tissue activity controls triglyceride clearance. Nat Med 2011; 17: 200-205.
• 3 Cannon B, Nedergaard J. Brown adipose tissue: function and physiological significance. Physiol Rev 2004; 84: 277-359.
• 4 Cypess AM, Lehman S, Williams G. et al. Identification and importance of brown adipose tissue in adult humans. N Engl J Med 2009; 360: 1509-1517.
• 5 Hadi M, Chen CC, Whatley M. et al. Brown fat imaging with ¹⁸F-6-fluorodopamine PET/CT, ¹⁸F-FDG PET/CT, and ¹²³I-MIBG SPECT: a study of patients being evaluated for pheochromocytoma. J Nucl Med 2007; 48: 1077-1083.
• 6 Madar I, Isoda T, Finley P. et al. ¹⁸F-fluorobenzyl triphenyl phosphonium: a noninvasive sensor of brown adipose tissue thermogenesis. J Nucl Med 2011; 52: 808-814.
• 7 Okuyama C, Ushijima Y, Kubota T. et al. ¹²³I-Metaiodobenzylguanidine uptake in the nape of the neck of children: likely visualization of brown adipose tissue. J Nucl Med 2003; 44: 1421-1425.
• 8 Ouellet V, Labbe SM, Blondin DP. et al. Brown adipose tissue oxidative metabolism contributes to energy expenditure during acute cold exposure in humans. J Clin Invest 2012; 122: 545-552.
• 9 Van Marken Lichtenbelt WD, Vanhommerig JW, Smulders NM. et al. Cold-activated brown adipose tissue in healthy men. N Engl J Med 2009; 360: 1500-1508.
• 10 Yeung HW, Grewal RK, Gonen M. et al. Patterns of ¹⁸F-FDG uptake in adipose tissue and muscle: a potential source of false-positives for PET. J Nucl Med 2003; 44: 1789-1796.