⁵⁷Co-Hematoporphyrin Accumulation by Experimental Tumors

Summary

The in vivo distribution of ⁵⁷Co-hematoporphyrin in adenocarcinoma BW10232-bearing mice has been studied. Tumor-bearing and normal animals exhibit similar patterns of radioactivity accumulation. Twenty-four hours after the administration of the radiocompound the ratios tumor to blood and tumor to muscle indicate a potential value of this radioactive porphyrin for the detection of some types of tumor.

Die in vivo-Verteilung von ⁵⁷Co-Hematoporphyrin in Adenokarzinom BW10232-tragenden Mäusen wurde untersucht. Tumortragende und normale Tiere zeigen ähnliche Anreicherungen von Radioaktivität. Vierundzwanzig Stunden nach der Verabreichung der radioaktiven Verbindung weist das Verhältnis Tumor zu Blut und Tumor zu Muskel auf einen möglichen Nutzen dieses radioaktiven Porphyrins für die Erkennung einiger Tumortypen hin.

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