Vet Comp Orthop Traumatol 1989; 02(04): 144-151
DOI: 10.1055/s-0038-1633214
Original Research
Schattauer GmbH

Multiple Enchondromatosis in the Dog

Clinical Findings
Ulrike Matis
*   From the Department of Veterinary Surgery, Ludwig-Maximilians-Universitat, Munich, the
,
K. Krauser
**   Institute of Veterinary Pathology, Freie Universitat, Berlin, and the
,
Dorothea Schwartz-Porsche
***   Department of Small Animals, Freie Universitat, Berlin
,
Afra v. Putzer-Brenig
*   From the Department of Veterinary Surgery, Ludwig-Maximilians-Universitat, Munich, the
› Author Affiliations
Further Information

Publication History

Publication Date:
09 February 2018 (online)

Summary

The clinical and radiological findings of three related Miniature Poodles with multiple enchondromatosis (Ollier’s disease) are presented. Persisting, in part ossified growth plate cartilage foci were found bilaterally in the humerus, radius, ulna, femur, tibia and fibula of each dog and in one dog in some metacarpal and metatarsal bones. The ribs and many vertebral bodies were also affected. There was evidently no bone formation in the sternebrae. All three dogs first attracted attention at the ages of four to six months, with spontaneous bilateral femoral neck fractures. The mode of inheritance of the condition is not yet clear, but based on the known pedigree data a dominant effect appears unlikely.

 
  • REFERENCES

  • 1 Bethge J F. Die Ollier’sche Krankheit. Dtsch med Wschr 1962; 87: 535-41.
  • 2 Jesserer H. Knochenkrankheiten. Urban & Schwarzenberg; Miinchen – Berlin – Wien: 1971
  • 3 Dominok G W, Knoch H G. Knochengeschwiilste und geschwulstahnliche Knochenerkrankungen. Gustav Fischer; Stuttgart: 1982
  • 4 Owen L N. Bone tumours in man and animal. Buterworth & Co; London: 1969
  • 5 Pool R R. Tumors of bone and cartilage. In: Moulton J. (ed). Tumors in domestic animals. 2nd edition. University of California Press; Berkeley, Los Angeles:
  • 6 Jubb K V F, Kennedy P C, Palmer N. Pathology of domestic animals. 2nd edition. volume 1 Academic Press; New York – London: 1985
  • 7 Dammrich K. Entwicklungsstorungen des Skeletts. In: Joest E. (ed) Handbuch der speziellen pathologischen Anatomie der Haustiere. 2. Auflage, Band IV. Paul Parey; Berlin – Hamburg: 1985
  • 8 Goldschmidt M H, Thrall D E. Benign bone tumors in the dog. In: Newton C D, Nunamaker D M. (eds). Textbook of small animal orthopedics. J. B. Lippincott Company: Philadelphia; 1985
  • 9 McGrath J T. Neurologic examination of the dog. 2nd edition. Lea & Febiger; Philadelphia: 1960
  • 10 Matis U, Waibl H. Proximale Femurfrakturen bei Katze und Hund. Tierarztl Prax 1985; (Suppl. 01) 159-78.
  • 11 Waibl H, Vollmerhaus B, Schebitz H, Matis U, Roos H. Zur Anatomie der Fugenknorpel langer Rohrenknochen des Hundes – 3. Mitteilung: Fugenknorpel des Os femoris. Kleintierpraxis 1981; 2: 89-94.
  • 12 Shapiro F. Ollier’s disease. An assessment of angular deformity, shortening and pathological fracture in 21 patients. J Bone Joint Surg 1982; 64 A(l) 95-103.
  • 13 Spranger J, Kemperdick H, Bakowski H, Opitz J M. Two peculiar types of enchondromatosis. Pediat Radiol 1978; 7: 215-9.
  • 14 De Laey J J, De Schryveer A, Kluysken P, Kunnen M. Orbital involvement in Ollier’s disease (multiple enchondromatosis). Int Ophthalmol 1982; 5: 149-54.
  • 15 Mainzer F, Minagi H, Steinbach H L. The variable manifestations of multiple enchondromatosis. Radiology 1971; 99: 377-88.
  • 16 Lange M, Hipp E. Lehrbuch der Orthopadie und Traumatologic, Band II. Erworbene Erkrankungen, Teil 2. F Enke; Stuttgart: 1976
  • 17 Zichner L. Konstitutionelle Knochenerkrankungen mit unbekannter Pathogenese. In: Jager M, Wirth C J. (Hrsg). Praxis der Orthopadie. Georg Thieme; Stuttgart – New York: 1986
  • 18 Adler C Z. Knochenkrankheiten. Diagnostik makroskopischer, histologischer und radiologischer Strukturveranderungen des Skeletts. Georg Thieme; Stuttgart: 1983
  • 19 Becker F, Becker W. Operative Behandlung der Tumoren der Knochen, der Gelenke und Weichteile des Stiitzgewebes. In: Holder E. (ed). Therapie maligner Tumoren, Hamoblastome, Bd. II. F Enke; Stuttgart: 1967
  • 20 Enderle A, Willert H G, Zichner L. Angeborene und erworbene Skelettsystemerkrankungen. In: Witt A N, Rettig H, Schleger K F, Hackenbroch M, Hupfauer W. (eds.) Orthopadie in Praxis und Klinik, 2. Auflage, Band III, Allgemeine Orthopadie, Teil I, Systemerkrankungen, Arthrogryposis und Stoffwechselerkrankungen. Georg Thieme; Stuttgart – New York: 1984
  • 21 Becker W. Knochentumoren. In: Jager M, Wirth C J. (eds). Praxis der Orthopadie. Georg Thieme; Stuttgart – New York: 1986
  • 22 Schipper J J, Rogge C W L. Ollier’s dyschondroplasia. Arch Chir Nederl 1974; 24: 319-29.
  • 23 Cocchi U. Krankheiten des Skelettsystems. In: Becker P E. (ed). Humangenetik, Band II. Georg Thieme; Stuttgart: 1964
  • 24 Plies G. Bewegungsapparat. In: Doerr W. (ed). Organpathologie, Band III. Georg Thieme; Stuttgart: 1974
  • 25 Muhr G, Ekkernkamp A. Enchondromatose (multiple Chondrome). In: Koslowski L, Bushe K A, Junginger Th, Schwemmle K. (eds). Lehrbuch der Chirurgie, 3. Auflage. Schattauer, Stuttgart – New York: 1988