Homeopathy 2018; 107(02): 150-154
DOI: 10.1055/s-0038-1637729
Original Research Article
The Faculty of Homeopathy

In Vitro Effects of Homeopathic Drugs on Cultured Escherichia coli

Jürgen Pannek
1  Department of Neuro Urology, Swiss Paraplegic Centre, Nottwil, Switzerland
Carmen Kurmann
2  Medical Laboratory, Swiss Paraplegic Centre, Nottwil, Switzerland
Esther Imbach
2  Medical Laboratory, Swiss Paraplegic Centre, Nottwil, Switzerland
Felix Amsler
3  Amsler Consulting, Basel, Switzerland
Susanne Pannek-Rademacher
4  Homöopathie-Pannek, Basel, Switzerland
› Author Affiliations
Funding This work was supported by Omida AG, Küssnacht am Rigi, Switzerland, who provided the homeopathic remedies.
Further Information

Publication History

08 November 2017

07 February 2018

Publication Date:
22 March 2018 (online)


Background Recurrent urinary tract infections (UTIs) are one of the most common morbidities in persons with neurogenic lower urinary tract dysfunction (NLUTD). Repetitive antibiotic treatment increases the risk of selecting multi-resistant bacteria. Homeopathic treatment has been reported to be effective in these patients. The mechanism of action, however, has not been clarified. Recently, a direct bactericidal effect of homeopathic remedies was shown. Such an effect is not in accordance with the general principles of homeopathy. To test this paradigm, we assessed the in vitro effects of homeopathic drugs on Escherichia coli derived from patients with NLUTD.

MethodsE. coli bacteria were harvested from 28 consecutive urine cultures. Standard antibiotic resistance testing and simultaneous resistance testing to homeopathic drugs (Apis mellifica, Cantharis, Causticum hahnemanni, Staphysagria, Nux vomica, Berberis vulgaris, and Lycopodium clavatum) in high (C30) potency were performed.

Results No significant inhibitory effect of any of the tested homeopathic drugs on any E. coli population could be found, irrespective of their sensitivity to antibiotic treatment.

Conclusion Based on our results, effects of homeopathic treatment of UTI are not based on direct bactericidal or bacteriostatic effects. These findings are in concordance with the hypothesis that homeopathy is based on host effects: for example, activation of the immune system, rather than effects on pathogens.