CC BY-NC-ND 4.0 · Laryngo-Rhino-Otol 2018; 97(S 02): S10
DOI: 10.1055/s-0038-1639751
Aerodigestivtrakt: Aerodigestive tract
Georg Thieme Verlag KG Stuttgart · New York

Eustachian Tube Dysfunction in 2 patients with localized Amyloidosis of the Nasopharynx and Eustachian Tube

AC Lauer
1  Klinikum Bielefeld Mitte, Bielefeld, Deutschland
C Quast
2  Klinikum Bielefeld Mitte, Bielefeld
D Ligum
2  Klinikum Bielefeld Mitte, Bielefeld
H Sudhoff
3  klinikum Bielefeld Mitte, Bielefeld
› Author Affiliations
Further Information

Publication History

Publication Date:
18 April 2018 (online)



Few cases of localized amyloidosis of the upper aerodigestive tract have been reported in literature.

Case presentation:

We present two cases of dilatory Eustachian tube dysfunction caused by localized nasopharyngeal amyloidosis.

Management and Outcome:

Diagnostic biopsies confirmed AL-amyloidosis of the Nasopharynx and Eustachian Tube protuberance. Both patients had undergone earlier treatments with grommets. Balloon dilation of the Eustachian tube was performed. The symptoms recurred in long-term follow-up.


Localised nasopharyngeal amyloidosis can be a rare cause of refractory Eustachian tube dysfunction and middle ear effusion. Histopathology has to confirm the diagnosis. Treatment options include grommets and balloon dilation for symptom control.