CC BY-NC-ND 4.0 · Laryngorhinootologie 2018; 97(S 02): S67
DOI: 10.1055/s-0038-1639944
Abstracts
Lernen am Fall / Learning based on Case Reports

Unsolved problems of the new TNM classification

AE Chaaban
1   HNO Klinikum Chemnitz, Chemnitz
,
J Oeken
2   HNO Klinkum Chemnitz, Chemnitz
,
T Salameh
3   Pathologie Klinikum Chemnitz, Chemnitz
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In the beginning of 2017, the 8th edition of the TNM classification of malignant tumors has been available. The classification for head and neck carcinoma regarding the p16-Expression changed.

However, the situation is unclear when the primary tumor and local lymph node metastasis shows a different expression of p16.

We introduce a patient with oropharyngeal carcinoma and ipsilateral cervical metastasis.

After tumorextraction and selective neck dissection on both sides, the histological result shows a p-16 positivity in the primary tumor, but this expression was not detected in the cervical lymph nodes. There was no evidence of a second carcinoma during the staging examination.

Using the 8th edition of the outgoing TNM classification, the classification of p16-positiv tumors has to be pT2, pN1, V0, R0 (UICC Stadium III) and for the p16-negative pT2, pN2a, V0, R0 (UICC stage IVa).

The question now arises which of the two named TNM classifications should be used in this case.



Publication History

Publication Date:
23 May 2018 (online)

© 2018. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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