Summary
Attempts were made to demonstrate ultrastructural changes of the tissue thromboplastin
after intravenous injection, as a model experiment on the pulmonary microthrombi formation
induced by the tissue thromboplastin circulating from venous return.
Concentrically arranged membrane structures of the injected thromboplastin disappeared
in extremely short time after the injection of the thromboplastin in rabbits. The
long sheet membrane of the injected thromboplastin was frequently seen as adhered
to the vascular endothelium or to the surface of blood corpuscles. Furthermore, fibrin
fibres were formed in contact with the long sheet membrane of the thromboplastin.
Membrane structures were not found anywhere in the control rabbits.
