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Thromb Haemost 1989; 62(04): 1100-1102
DOI: 10.1055/s-0038-1647125
Original Article
Platelets
Schattauer GmbH Stuttgart

Human Platelets Contain mRNA Transcripts for Platelet Factor 4 and Actin

Jane Sottile
The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
,
Deane F Mosher
The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
,
Jan Fullenweider
The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
,
James N George
The Departments of Physiological Chemistry and Medicine, University of Wisconsin, Madison, WI, USA
› Author Affiliations
Further Information

Publication History

Received 21 June 1989

Accepted 10 August 1989

Publication Date:
24 July 2018 (online)

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Summary

RNAs from a number of cells, including platelets, were analyzed by Northern blotting for the presence of transcripts to four platelet proteins - actin, thrombospondin, fibronectin, and platelet factor 4. RNA from platelets contains considerable amounts of mRNA for platelet factor 4, easily detectable mRNA for actin, and traces of mRNA for thrombospondin. mRNA for platelet factor 4 was not detected in human lymphocytes or in any of 5 human cell lines.

Keywords

Platelet mRNA - Platelet factor 4 - Thrombospondin
 

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