Thromb Haemost 1990; 64(01): 099-103
DOI: 10.1055/s-0038-1647261
Review Article
Schattauer GmbH Stuttgart

The Role of Platelet-Activating Factor in Endothelial Cells

Stephen M Prescott
The Nora Eccles Harrison Cardiovascular Research and Training institute and the Departments of Internal Medicine and Biochemistry university of Utah, salt Lake city, Utah, U. S. A.
,
Thomas M McIntyre
The Nora Eccles Harrison Cardiovascular Research and Training institute and the Departments of Internal Medicine and Biochemistry university of Utah, salt Lake city, Utah, U. S. A.
,
Guy A Zimmerman
The Nora Eccles Harrison Cardiovascular Research and Training institute and the Departments of Internal Medicine and Biochemistry university of Utah, salt Lake city, Utah, U. S. A.
› Author Affiliations
Further Information

Publication History

Received 07 February 1990

Accepted after revision 19 April 1990

Publication Date:
25 July 2018 (online)

 
  • References

  • 1 Prescott SM, Zimmerman GA, McIntyre TM. Human endothelial cells in culture produce platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when stimulated with thrombin. Proc Natl Acad Sci USA 1984; 81: 3534-3538
  • 2 Camussi G, Aglietta M, Malavasi F, Tetta C, Piacebello W, Sanavio F, Bussolino F. The release of platelet-activating factor from human endothelial cells in culture. J Immunol 1983; 131: 2397-2403
  • 3 Whatley RE, Nelson P, Zimmerman GA, Stevens DL, Parker CJ, McIntyre TM, Prescott SM. The regulation of platelet-activating factor production in endothelial cells - the role of calcium and protein kinase C. J Biol Chem 1989; 264: 6325-6333
  • 4 Hirafuji M, Mencia-Huerta JM, Benveniste J. Regulation of PAF-acether (platelet-activating factor) biosynthesis in cultured human vascular endothelial cells stimulated with thrombin. Biochim Biophys Acta 1987; 930: 359-369
  • 5 Ghigo D, Bussolino F, Garbarino G, Heller R, Turrini F, Pescarmona G, Cragoe Jr EJ, Pegararo L, Bosia A. Role of Na+/H+ exchange in thrombin-induced platelet-activating factor production by human endothelial cells. J Biol Chem 1986; 263: 19437-19446
  • 6 Chilton FH, Ellis JM, Olson SC, Wykle RL. 1-O-Alkyl-2-arachidonoyl-sn-glycero-3-phosphocholine: A common source of platelet-activating factor and arachidonate in human polymorphonuclear leukocytes. J Biol Chem 1984; 259: 12014-12019
  • 7 Zimmerman GA, McIntyre TM, Prescott SM. Production of platelet-activating factor by human vascular endothelial cells: Evidence for a requirement for specific agonists and modulation by prostacyclin. Circulation 1985; 76: 271-280
  • 8 Snyder F. Introduction. Historical aspects of alkyl lipids and their biologically active forms (ether lipids, platelet-activating factor, and antihypertensive renal lipids). In: Platelet Activating Factor and Related Lipid Mediators Snyder F. (ed). Plenum Publishing Corporation; New York: 1987: 1
  • 9 McIntyre TM, Zimmerman GA, Satoh K, Prescott SM. Cultured endothelial cells synthesize both platelet-activating factor and prostacyclin in response to histamine, bradykinin, and adenosine triphosphate. J Clin Invest 1985; 76: 271-280
  • 10 McIntyre TM, Zimmerman GA, Prescott SM. Leukotrienes C4 and D4 stimulate human endothelial cells to synthesize platelet-activating factor and bind neutrophils. Proc Natl Acad Sci USA 1986; 83: 2204-2208
  • 11 Whatley RE, Zimmerman GA, McIntyre TM, Prescott SM. Endothelium from diverse vascular sources synthesizes platelet-activating factor. Arteriosclerosis 1988; 8: 321-331
  • 12 Lynch JM, Henson PM. The intracellular retention of newly synthesized platelet-activating factor. J Immunol 1986; 137: 2653-2661
  • 13 Stewart AG, Dubbin PN, Harris T, Dusting GJ. Evidence for an intracellular action of platelet-activating factor in bovine cultured aortic endothelial cells. Br J Pharmacol 1989; 96: 503-505
  • 14 Bussolino F, Camussi G, Baglioni C. Synthesis and release of platelet-activating factor by human vascular endothelial cells treated with tumor necrosis factor or interleukin Ia. J Biol Chem 1988; 263: 11856-11861
  • 15 Zavoico GB, Ewenstein BM, Schafer AI, Pober JS. IL-1 and related cytokines enhance thrombin-stimulated PGI2 production in cultured endothelial cells without affecting thrombin-stimulated von Wille-brand factor secretion or platelet-uctivating factor biosynthesis. J Immunol 1989; 142: 3993-3999
  • 16 Zimmermann GA, McIntyre TM, Prescott SM. Thrombin stimulates the adherence of neutrophils to human endothelial cells in vitro. J Clin Invest 1985; 76: 2235-2246
  • 17 Lewis MS, Whatley RE, Cain P, McIntyre TM, Prescott SM, Zimmerman GA. Hydrogen peroxide stimulates the synthesis of platelet-activating factor by endothelium and induces endothelial cell-dependent neutrophil adhesion. J Clin Invest 1988; 82: 2045-2055
  • 18 Zimmerman GA, McIntyre TM, Mehra M, Prescott SM. Endothelial cell-associated platelet-activating factor: A novel mechanism for signaling intercellular adhesion. J Cell Biol 1990; 110: 529-540
  • 19 Bevilacqua MP, Stengelin S, Gimbrone Jr MA, Seed B. Endothelial leukocyte adhesion molecule 1: An inducible receptor for neutrophils related to complement regulatory proteins and lectins. Science 1989; 243: 1160-1165
  • 20 Breviario F, Bertocchi F, Dejana E, Bussolino F. IL-1-induced adhesion of polymorphonuclear leukocytes to cultured human endothelial cells. J Immunol 1988; 141: 3391-3397
  • 21 Banks JB, Wykle RL, O’Flaherty JT, Lumb RH. Evidence for protein-catalyzed transfer of platelet activating factor by macrophage cytosol. Biochim Biophys Acta 1988; 961: 48-52
  • 22 Hattori R, Hamilton KK, Fugate RD, McEver RP, Sims PJ. Stimulated secretion of endothelial von Willebrand factor is accompanied by rapid redistribution to the cell surface of the intracellular granule membrane protein GMP-140. J Biol Chem 1989; 264: 7768-7771
  • 23 Geng J-G, Bevilacqua MP, Moore KL, McIntyre TM, Prescott SM, Kim JM, Bliss GA, Zimmerman GA, McEver RP. GMP-140 mediates rapid neutrophil adhesion to activated endothelium. Nature 1990; 343: 757-760
  • 24 VerCellotti GM, Wickham NW R, Gustafson KS, Yin HQ, Hebert M, Jacob HS. Thrombin-treated endothelium primes neutrophil functions: Inhibition by platelet-activating factor receptor antagonists. J Leukocyte Biol 1989; 45: 483-490
  • 25 Bochner BS, Peachell PT, Brown KE, Schleimer RP. Adherence of human basophils to cultured umbilical vein endothelial cells. J Clin Invest 1988; 81: 1355-1364
  • 26 Lamas AM, Mulroney CM, Schleimer RP. Studies on the adhesive interaction between purified human eosinophils and cultured vascular endothelial cells. J Immunol 1988; 140: 1500-1505
  • 27 Kimani G, Tonnesen MG, Henson PM. Stimulation of eosinophil adherence to human vascular endothelial cells in vitro by platelet-activating factor. J Immunol 1988; 140: 3161-3166