Coagulation Factors of the Newborn and His Mother

L Biland; F Duckert

doi:10.1055/s-0038-1648106

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1973; 29(03): 644-651
DOI: 10.1055/s-0038-1648106

Original Article

Schattauer GmbH

Coagulation Factors of the Newborn and His Mother

L Biland

¹Department of Internal Medicine, First University Medical Clinic, Coagulation and Fibrinolysis Laboratories, Kantonsspital, Basle, Switzerland

,

F Duckert

¹Department of Internal Medicine, First University Medical Clinic, Coagulation and Fibrinolysis Laboratories, Kantonsspital, Basle, Switzerland

› Author Affiliations

Abstract

Summary

In 50 mothers and their newborns 13 parameters of blood coagulation and fibrinolysis have been investigated. No correlation was found between the activity in the mother’s blood and in the cord blood.

The activity of the factors V, VIII and IX can be so low in the blood of the normal newborn that it is not possible to detect a hereditary coagulopathy early at birth time. Fibrinogen and factor XIII make an exception. The factor XIII is normal in the cord blood, even higher than in the mother’s blood.

The values of fibrinogen measured with different methods disagree (Table 1). These results are discussed in connection with the antithrombin II, antithrombin III, split products and plasminogen values.

Full Text

References

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