Measurement of Activated Factor VII Using Soluble Mutant Tissue Factor -Proposal for Standardization

• References

• 1 Morrissey JH, Macik BG, Neuenschwander PF, Comp PC. Quantitation of activated factor VII levels in plasma using a tissue factor mutant selectively deficient in promoting factor VII activation. Blood 1993; 81: 734-744
• 2 Hubbard AR, Parr LJ. Potency estimation of activated factor VII concentrates. Thromb Haemost 1991; 65: 1160
• 3 Kitchen S, Malia RG, Preston FE. A comparison of methods for the measurement of activated factor VII. Thromb Haemost 1992; 68: 301-395
• 4 Hedner U, Ljundberg J, Lund-Hansen T. Comparison of the effect of plasma-derived and recombinant human FVIIa in vitro and in a rabbit model. Blood Coag Fibrinol 1990; 1: 145-152
• 5 WHO Expert Committee on Biological Standardization. Forty-third report. WHO Technical Report Series, No 840 1994