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Thromb Haemost 1980; 44(01): 030-031
DOI: 10.1055/s-0038-1650074
Original Article
Schattauer GmbH Stuttgart

Labelling of Blood Platelets with Stable Tracers

D Del Principe
1)   The I Department of Pediatrics, University of Rome, Italy
,
R Cesareo
2)   The Istituto di Fisica, Facoltà di Ingegneria, University of Rome, Italy
,
B M Tallarida
1)   The I Department of Pediatrics, University of Rome, Italy
,
M G Ciancarelli
3)   The Cattedra di Fisiologia, L. Istituto di Medicina e Chirurgia, L'Aquila, Italy
,
M Ricci
1)   The I Department of Pediatrics, University of Rome, Italy
,
G Mancuso
1)   The I Department of Pediatrics, University of Rome, Italy
› Author Affiliations
Further Information

Publication History

Received 08 January 1980

Accepted 18 June 1980

Publication Date:
13 July 2018 (online)

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Summary

Half-time values of platelets labelled with stable rubidium are compared to those of platelets labelled with Cr51. Platelets labelled with stable rubidium are assayed by a very simple version of the X-Ray fluorescence equipment. The mean quantity of rubidium incorporated by the cells is of about some µg Rb per ml blood.

The in vitro half-time of human Rb labelled platelets stored at 22° C is 41.2 ± 3h compared with the value 44.8 ± 3h for platelets labelled with Cr51, as deduced by six experiments. The in vivo half-time of rabbit platelets labelled with stable rubidium is 22 ± 3h compared with the value 18 ± 3h of platelets labelled with Cr51; ten experiments were carried out.

Key words

Blood platelets - Survival; stable tracers
 

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