Thromb Haemost 1981; 45(03): 197-199
DOI: 10.1055/s-0038-1650168
Original Article
Schattauer GmbH Stuttgart

Evaluation of Some Platelet Parameters in a Group of Elderly People

P Sie
*   The Laboratoire d'Hémostase, Centre Régional de Transfusion Sanguine, Toulouse, France
,
J Montagut
**   The Centre de Gérontologie, Hôpital La Grave, Toulouse, France
,
M Blanc
**   The Centre de Gérontologie, Hôpital La Grave, Toulouse, France
,
B Boneu
*   The Laboratoire d'Hémostase, Centre Régional de Transfusion Sanguine, Toulouse, France
,
C Caranobe
*   The Laboratoire d'Hémostase, Centre Régional de Transfusion Sanguine, Toulouse, France
,
J C Cazard
**   The Centre de Gérontologie, Hôpital La Grave, Toulouse, France
,
R Biermé
*   The Laboratoire d'Hémostase, Centre Régional de Transfusion Sanguine, Toulouse, France
› Institutsangaben
Weitere Informationen

Publikationsverlauf

Received 30. Juli 1980

Accepted 15. Oktober 1980

Publikationsdatum:
06. Juli 2018 (online)

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Summary

Platelet production time (PPT), plasmatic β-thromboglobulin (β-TG), platelet density distribution, and mepacrine labelled granular content of the platelets were simultaneously determined in a group of elderly subjects. Vascular deterioration, assessed by the history and clinical examination, was variable in extension and severity. PPT was slightly but not significantly shortened, whereas the raised β-TG level and diminished platelet density and granular content suggested an in vivo release reaction process. The results are not correlated with the apparent severity of vascular deterioration, and the release reaction may not be solely related to enhanced platelet-vessel wall interactions.