Thromb Haemost 1996; 76(05): 817-818
DOI: 10.1055/s-0038-1650669
Letters to the Editor
Schattauer GmbH Stuttgart

The Pathogenesis of the Antiphospholipid Syndrome

M Greaves
,
M B Hill
,
J Phipps
,
P Hughes
,
I Ford
Further Information

Publication History

Received 20 May 1996

Accepted 22 July 1996

Publication Date:
11 July 2018 (online)

 
  • References

  • 1 Arnout J. The pathogenesis of the antiphospholipid syndrome: a hypothesis based on parallelisms with heparin-induced thrombocytopenia. Thromb Haemost 1996; 75: 536-541
  • 2 Greaves M, Hughes P, Malia RG, Henderson FI, Lindsey NJ. Autoimmune thrombotic disease. Relative roles of antiphospholipid and anti-endothelial cell activity. Thromb Haemost 1993; 69: 953
  • 3 Malia RG, Kitchen S, Greaves M, Preston FE. Inhibition of activated protein C and its co-factor Protein S by antiphospholipid antibodies. Brit J Haematol 1990; 76: 101-107
  • 4 Hampton KK, Preston FE, Greaves M. Resistance to activated protein C. N Engl J Med 1994; 331: 130
  • 5 Del Papa N, Guidali L, Spatola L, Bonara P, Borghi MO, Tincani A, Balestrieri G, Meroni PL. Relationship between anti-phospholipid and anti-endothelial cell antibodies III: beta2 glycoprotein 1 mediates the antibody binding to endothelial membranes and induces expression of adhesion molecules. Clin Exper Rheumatol 1995; 13: 179-185
  • 6 Hill MB, Phipps JL, Malia RG, Greaves M, Hughes P. Characterisation and specificity of anti-endothelial cell membrane antibodies and their relationship to thrombosis in primary antiphospholipid syndrome (APS). Clin Exp Immunol 1995; 102: 368-372
  • 7 Hill MB, Greaves M, Phipps JL, Milford-Ward A, Malia RG, Hughes P. Characterisation and prothrombotic significance of anti-endothelial antibodies and their relationship to antiphospholipid antibodies in SLE and PAPS. Brit. J. Haematol 1995; 89 (Suppl. 01) 8
  • 8 Hill MB, Phipps JL, Hughes P, Greaves M. Potentially pathogenic anti-vascular endothelial cell antibodies in primary antiphospholipid syndrome (APS), SLE and scleroderma: differences in binding to umbilical vein and microvascular endothelial cells. Blood Coag Fibrinolysis 1996; (07) 3: 379
  • 9 Lindsey NJ, Dawson RA, Henderson FI, Greaves M, Hughes P. Stimulation of von Willebrand factor antigen release by immunoglobulin from thrombosis prone patients with systemic lupus eythematosus and the antiphospholipid syndrome. Br J Rheumatol 1993; 32: 123-126
  • 10 Holt CM, Lindsey N, Moult LJ, Malia RG, Greaves M, Hume A, Rowell NR, Hughes P. Antibody dependent cellular cytotoxicity of vascular endothelium; characterisation and pathogenic associations in systemic sclerosis. Clin Exp. Immunol 1989; 78: 359-365
  • 11 Nimpf J, Bevers EM, Bomans PHH, Till U, Wurm H, Kostner GM, Zwaal RFA. Prothrombinase activity of human platelets is inhibited by beta2-gly-coprotein 1. Biochem. Biophys Acta 1986; 884: 142-149