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Thromb Haemost 1981; 46(03): 626-628
DOI: 10.1055/s-0038-1653433
Original Article
Schattauer GmbH Stuttgart

Dialysis and Renal Transplant in a Hemophiliac

Authors

  • Edward D Gomperts

    The Divisions of Dialysis, Transplant and Hematology, Oncology, Department of Pediatrics, Childrens Hospital of Los Angeles and University of Southern California, Los Angeles, California, U.S.A

  • Mohammed H Malekzadeh

    The Divisions of Dialysis, Transplant and Hematology, Oncology, Department of Pediatrics, Childrens Hospital of Los Angeles and University of Southern California, Los Angeles, California, U.S.A

  • Richard N Fine

    The Divisions of Dialysis, Transplant and Hematology, Oncology, Department of Pediatrics, Childrens Hospital of Los Angeles and University of Southern California, Los Angeles, California, U.S.A
Further Information

Publication History

Received 16 March 1981

Accepted 05 August 1981

Publication Date:
05 July 2018 (online)

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Summary

Hemodialysis was initiated in a mild-moderate hemophiliac at 15 years of age. Hematuria had been a frequent and persisting feature from the age of five years without documented cause. Anemia and proteinuria was first detected at 13 years. A cadaver donor renal transplant was carried out after three months of hemodialysis. Massive intravesical bleeding complicated the immediate post-transplantation period. The allograft rejected after three months and the patient was maintained for eight years on home hemodialysis. A second cadaver donor allograft was carried out at 23 years of age. Again, massive intravesical hemorrhage was a problem post-transplant. The allograft is currently functioning 27 months post-transplant. Factor VIIIc activities have fluctuated between 5% and 40% in the absence of factor infusions.

Keywords

Transplant - Hemophilia
 

  • References

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