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Thromb Haemost 1971; 25(02): 234-240
DOI: 10.1055/s-0038-1654298
Originalarbeiten – Original Articles – Travaux Originaux
Schattauer GmbH

Defective Collagen-Induced Platelet Aggregation in a Normal Population

J. W ten Cate
*   Department of Haematology of the University Hospital “Wilhelmina Gasthuis”, Amsterdam, The Netherlands
,
S. I de Vries
*   Department of Haematology of the University Hospital “Wilhelmina Gasthuis”, Amsterdam, The Netherlands
,
J. J Sixma
**   The Department of Internal Medicine of the University Hospital, Utrecht, The Netherlands
,
W van Berkel
**   The Department of Internal Medicine of the University Hospital, Utrecht, The Netherlands
› Institutsangaben
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Publikationsverlauf

Publikationsdatum:
24. Juli 2018 (online)

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Summary

Systemic studies on platelet functions of normal healthy individuals were carried out in two independent centres. Both samples of 40 volunteers comprised several individuals (Amsterdam 3 and Utrecht 5 individuals) with a syndrome consisting of an absent collagen-induced platelet aggregation, a reversible ADP-aggregation and frequently a decreased platelet retention in the glass bead column. Occasionally the platelet factor-3 availability was decreased.

 

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