Some Observations on the Coagulation Defect During Treatment with the Anticoagulant “Sintrom”

H. J Vermeulen; S. A ten Bokkel Huinink; K. S Radhakishun

doi:10.1055/s-0038-1654373

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1959; 03(01): 092-097
DOI: 10.1055/s-0038-1654373

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

Some Observations on the Coagulation Defect During Treatment with the Anticoagulant “Sintrom”

Authors

H. J Vermeulen

¹Medical Department, Municipal Hospital Bergweg, Rotterdam (Head: Dr. S. A. ten Bokkel Huinink)
S. A ten Bokkel Huinink

¹Medical Department, Municipal Hospital Bergweg, Rotterdam (Head: Dr. S. A. ten Bokkel Huinink)
K. S Radhakishun

¹Medical Department, Municipal Hospital Bergweg, Rotterdam (Head: Dr. S. A. ten Bokkel Huinink)

Abstract

Conclusions

1. The decrease of activity of prothrombin, occuring during administration of “Sintrom”, becomes only manifest when the activity of “factor VII” has fallen to less than half its normal value.

2. The behaviour of the thrombin time is the manifestation of an important difference between the coagulation defect in hepatitis and that on administration of Sintrom.

Full Text

References

References
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