Thromb Haemost 1960; 4(03): 323-330
DOI: 10.1055/s-0038-1654513
Originalarbeiten — Original Articles — Travaux Originaux
Schattauer GmbH

A Rapid Quantitative Assay of Factor VIII (AHG) Without the Use of Haemophilia A Plasma

Ernst G. Jung
1   Coagulation Laboratory (Prof. F. Koller) of the Department of Medicine (Prof. P. H. Rossier) University of Zurich, Switzerland
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Publication Date:
17 June 2018 (online)

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Summary

A new method for the quantitative determination of factor VIII (AHG) without using haemophilia A plasma as test substrate has been described. The comparison to Geiger et al. shows a good concordance. The normal range of factor VIII in adults is 50—150% (normal plasma taken as 100%) and the average value of healthy newborns is 78%. This is compared to the average values of the other clotting factors in newborns. Factor VIII is not affected by deficient vitamin K resorption.