Z Gastroenterol 2018; 56(05): e43-e44
DOI: 10.1055/s-0038-1654648
POSTER
Hepatologie
Georg Thieme Verlag KG Stuttgart · New York

Project presentation: Outcome and survival of patients with acute variceal bleeding at the UK St. Pölten, a register

F Riedl
1   UK St. Pölten, 2. Medizinische Abteilung, Sankt Pölten, Austria
,
M Stättermayer
1   UK St. Pölten, 2. Medizinische Abteilung, Sankt Pölten, Austria
,
N Pfisterer
2   Krankenanstalt Rudolfstiftung, Wien, Austria
,
M Trauner
3   AKH Wien, III. Medizinische Abteilung, Wien, Austria
,
A Mayer
1   UK St. Pölten, 2. Medizinische Abteilung, Sankt Pölten, Austria
,
T Reiberger
4   III. Medizinische Abteilung, AKH, Wien, Austria
,
A Maieron
1   UK St. Pölten, 2. Medizinische Abteilung, Sankt Pölten, Austria
› Author Affiliations
Further Information

Publication History

Publication Date:
09 May 2018 (online)

 

Background:

Despite significant improvements in the management of acute variceal bleeding (AVB)- over the last decades, AVB remains associated with considerable morbidity and mortality. By implementing a prospective AVB-registry, we aim to improve evidence-based patient management.

Methods:

A prospective registry recruiting consecutive patients with AVB at the UK St. Pölten was implemented since 01/2018. Events of interest are (i) failure to control bleeding within 5 days, (ii) AVB-related mortality within 6 weeks, and (iii) overall survival. Patient's characteristics, laboratory parameters and implementation of secondary prophylaxis are documented.

Results:

N = 7 patients (male: 6 (86%); median MELD-score of 12, Child-Pugh A: 2, B: 5) have been included at the time of abstract submission. Alcoholic liver disease was the most common etiology of liver cirrhosis (n = 5,71%). In n = 4 (57%) patients the bleeding event presented a recurrent episode of AVB. All bleedings were endoscopically controlled and there was no failure to control AVB. TIPS implantation for secondary prophylaxis was performed in n = 3 (43%) patients and n = 1 preexisting TIPS with stentocclusion was reopened. All other n = 3 (43%) patients were started on secondary prophylaxis with combined endoscopic band ligation (EBL) and non-selective betablockers, including n = 1 patient who is listed for liver transplantation. Data on additional patients, AVB-related mortality, and long-term outcome will be reported at the annual meeting.

Conclusion:

At this early stage of observation, we documented a high incidence of AVB at our center. No failure to control bleeding was observed so far. Most importantly, TIPS implantation is regularly performed for secondary prophylaxis. In conclusion, this register helps to improve surveillance of guideline-conform treatment and outcome of patients with AVB. Extension to other Austrian centers is in progress.