A Modified Method for the Assay of Factor IX

N. N Sen; Radharani Sen; K. W. E Denson; Rosemary Biggs

doi:10.1055/s-0038-1655032

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1967; 18(01/02): 241-251
DOI: 10.1055/s-0038-1655032

Originalarbeiten — Original Articles — Travaux Originaux

Schattauer GmbH

A Modified Method for the Assay of Factor IX

N. N Sen^*

¹Medical Research Council, Blood Coagulation Research Unit, Churchill Hospital, Oxford

,

Radharani Sen^**

¹Medical Research Council, Blood Coagulation Research Unit, Churchill Hospital, Oxford

,

K. W. E Denson

¹Medical Research Council, Blood Coagulation Research Unit, Churchill Hospital, Oxford

,

Rosemary Biggs

¹Medical Research Council, Blood Coagulation Research Unit, Churchill Hospital, Oxford

› Author Affiliations

Abstract

Summary

A modification of the method for the assay of factor IX proposed by Biggs et al. (1961) (1) is described. The modification is likely to prove more reliable than the original method.

Full Text

References

References
1 Biggs R, Bidwell E, Handley D. A, Macfarlane R. G, Trueta J, Elliot-Smith A, Dike G. W. R, Ash B. J. The preparation and assay of a Christmas factor (Factor IX) concentrate and its use in the treatment of two patients. Brit. J. Haemat. 07: 349 1961;
2 Biggs J. R, Macfarlane R. G. Human Blood Coagulation and Its Disorders. 3rd. Ed.. Blackwell Scientific Publications; Oxford: 1962
3 Gattan A. D, Denson K. W. E. The interaction of contact factor and factor IX. Thrombos. Diathes. haemorrh. (Stuttg) 11: 155 1964;
4 Nossel H. L. The Contact Phase of Blood Coagulation. Blackwell Scientific Publications; Oxford: 1964