Thrombosis and Haemostasis, Table of Contents Thromb Haemost 1967; 18(03/04): 525-531DOI: 10.1055/s-0038-1655061 Originalarbeiten — Original Articles — Travaux Originaux Schattauer GmbH Contact Activation in the Extrinsic Blood Clotting System R Altman * 1 Haematology Section of the Department of Internal Medicine, University Hospital, Leyden (The Netherlands) , H. C Hemker 1 Haematology Section of the Department of Internal Medicine, University Hospital, Leyden (The Netherlands) › Author Affiliations Recommend Article Abstract Buy Article Summary After contact activation, factor XII can convert factor VII into its active form. Factor XI enhances this action but appears not to be a compulsatory part of the system. The short circuit of the intrinsic system constituted by this pathway may be important in triggering the intrinsic coagulation system. Full Text References References 1 Hemker H. G, Altman R, Siepel T, Loeliger E. A. Thrombosis Diathes. haemorrh. (Stuttg.) 17: 349 1967; 2 Shanberge J. N, Matsuoka T. Thrombos. Diathes. haemorrh. (Stuttg) 15: 442 1966; 3 Vroman L. Thrombos. Diathes. haemorrh. (Stuttg) 10: 455 1963; 4 Nossel H. L. The contact phase of blood coagulation. Blackwell Scientific. Publications; Oxford: 1964 5 de Vries S. I, Braat-van Straaten J. Thrombos. Diathes. haemorrh. (Stuttg) 11: 167 1964; 6 Soulier J. P, Prou-Wartelle O. Brit. J. Haemat. 06: 88 1960; 7 Niewiarowski S, Stachurska J, Wegrzynowicz Z. Thrombos. Diathes. haemorrh. (Stuttg). 07: 514 1962; 8 Waaler B. A. Contact activation in the Intrinsic Blood Clotting System. Oslo University Press; Oslo: 1959 9 Rapaport S. I, Hjort P. F, Patch M. J. Scand. J. clin. Lab. Invest. 17 (suppl. 84): 88 1965; 10 Newcomb T. F, Hoshida M. Scand. J. clin. Lab. Invest 17 (suppl. 84): 61 1965; 11 Bergsagel D. E, Nockolds E. R. Brit. J. Haemat. 11: 395 1965; 12 Käser-Glanzmann R, Lüscher E. F. Thrombos. Diathes. haemorrh. (Stuttg) 07: 480 1962;
