Hemarthroses and Warfarin: Joint Destruction with Anticoagulation

W Abe Andes; J Ollie Edmunds

doi:10.1055/s-0038-1657358

Thrombosis and Haemostasis, Table of Contents

Thromb Haemost 1983; 49(03): 187-189
DOI: 10.1055/s-0038-1657358

Original Article

Schattauer GmbH Stuttgart

Hemarthroses and Warfarin: Joint Destruction with Anticoagulation

W Abe Andes

The Departments of Medicine and Orthopaedics, Tulane University School of Medicine, The Veterans Administration Hospital of New Orleans and The Louisiana Comprehensive Hemophilia Care Center, New Orleans, Louisiana, U.S.A.

,

J Ollie Edmunds

The Departments of Medicine and Orthopaedics, Tulane University School of Medicine, The Veterans Administration Hospital of New Orleans and The Louisiana Comprehensive Hemophilia Care Center, New Orleans, Louisiana, U.S.A.

› Author Affiliations

Abstract

PDF Download

Summary

A 56 year old man was seen because of recurrent right shoulder hemarthroses and a superior vena caval syndrome. Intermittent symptoms had occurred for six years and resulted in marked destructive changes in the right shoulder. Arthroscopy added pathological evidence of this unusual mechanism of arthropathy. Patients on anticoagulants deserve close attention to symptoms of occult bleeding.

Keywords

Warfarin - Hemarthroses - Anticoagulation - Arthropathy

PDF (769 kb)

References

References
1 Houghton GR, Duthie RB. Orthopedic problems in hemophilia. Clin Orthop 1979; 138: 197-216
2 Hasselbacher P, Schimmer BM, Weinberger A. Hemarthroses with sodium warfarin and heparin. Arthritis Rheum 1978; 21: 740
3 Jaffer AM, Schmid FR. Hemarthroses associated with sodium warfarin. J Rheumatol 1977; 4: 215-217
4 McLauglin GE, McCarty Jr DR, Segal BL. Hemarthrosis complicating anticoagulant therapy. Report of three cases. JAMA 1966; 196: 202-203
5 Wild JH, Zvaifler NJ. Hemarthrosis associated with sodium warfarin therapy. Arthritis Rheum 1976; 19: 98-102
6 Katz AL, Alepa FP. Hemarthrosis secondary to heparin therapy. Arthritis Rheum 1976; 19: 966
7 Mayer JW. Hemarthrosis in a heparinized patient. Arthritis Rheum 1977; 20: 901
8 Hale WB, Moorthy AV, Middleton WS. Hemarthrosis from heparin therapy. JAMA 1980; 244: 30
9 Sjamsoedin LJ M, Heijnen L, Mauser-Bunschoten EP, Van GeijlswijkJ L, Van HouwelingenH, Van AstenP, Sixma JJ. The effect of activated prothrombin-complex concentrate (FEIBA) on joint and muscle bleeding in patients with hemophilia A and antibodies to factor Vlll. A double-blind clinical trial. N Engl J Med 1981; 305: 717-721
10 Lusher JM, Shapiro SS, Palasaak JE, Rao AV, Levine PH, Blatt PM. Efficacy of prothrombin-complex concentrates in hemophiliacs with antibodies for factor VIII. N Engl J Med 1980; 303: 421-425
11 Biggers JA, Remmers AR, Classford DM, Sarles HE, Lindley JD, Fish JC. The risk of anticoagulation in hemodialysis patients. Nephron 1977; 18: 109-113
12 Gallop PM, Lian JB, Hauschka PV. Carboxylated calcium-binding proteins and vitamin K. N Engl J med 1980; 302: 1460-1466