Mechanisms Initiating Platelet Thrombus Formation

• References

• 1 Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (1). N Engl J Med 1992; 326: 242-250
• 2 Fuster V, Badimon L, Badimon JJ, Chesebro JH. The pathogenesis of coronary artery disease and the acute coronary syndromes (2). N Engl J Med 1992; 326: 310-318
• 3 Kroll MH, Heliums JD, Mclntire LV, Schafer AI, Moake JL. Platelets and shear stress. Blood 1996; 88: 1525-1541
• 4 Tangelder GJ, Slaaf DW, Arts T, Reneman RS. Wall shear rate in arterioles in vivo: least estimates from platelet velocity profiles. Am J Physiol 1988; 254: H1059-H1064
• 5 Back CH, Radbill JR, Crawford DW. Analysis of pulsatile viscous blood flow through diseased coronary arteries of man. J Biomech 1977; 10: 339-353
• 6 Ruggeri ZM, Ware J. von Willebrand factor. FASEB J 1993; 07: 308-316
• 7 Cruz MA, Yuan H, Lee JR, Wise RJ, Handin RI. Interaction of the von Willebrand factor (vWF) with collagen. J Biol Chem 1995; 270: 10822-10827
• 8 Fujimura Y, Titani K, Holland LZ, Roberts JR, Kostel P, Ruggeri ZM, Zimmerman TS. A heparin-binding domain of human von Willebrand factor. Characterization and localization to a tryptic fragment extending from amino acid residue Val-449 to Lys-728. J Biol Chem 1987; 262: 1734-1739
• 9 Christophe O, Obert B, Meyer D, Girma J. The binding domain of von Willebrand factor to sulfatides is distinct from those interacting with glycoproteinames lb, heparin, and collagen and resides between amino acid residues Leu 512 and Lys 673. Blood 1991; 78: 2310-1217
• 10 Denis C, Baruch D, Kielty CM, Ajzenberg N, Christophe O, Meyer D. Localization on von Willebrand factor binding domains to endothelial extracellular matrix and to type VI collagen. Arterioscl Thromb 1993; 13: 398-406
• 11 Fujimura Y, Titani K, Holland LZ, Russell SR, Roberts JR, Elder JH, Ruggeri ZM, Zimmerman TS. von Willebrand factor. A reduced and alkylated 52/48 kDa fragment beginning at amino acid residue 449 contains the domain interacting with platelet glycoprotein lb. J Biol Chem 1986; 261: 381-385
• 12 Savage B, Saldivar E, Ruggeri ZM. Initiation of platelet adhesion by arrest onto fibrinogen or translocation on von Willebrand factor. Cell 1996; 84: 289-297
• 13 Savage B, Ruggeri ZM. Selective recognition of adhesive sites in surface-bound fibrinogen by GP IIb-IIIa on nonactivated platelets. J Biol Chem 1991; 266: 11227-11233
• 14 Saelman EUM, Nieuwenhuis HK, Hese KM, de Groot PG, Heijnen HFG, Sage EH, Williams S, McKeown L, Gralnick HR, Sixma JJ. Platelet adhesion to collagen types I through VIII under conditions of stasis and flow is mediated by GPIa/IIa (α₂β₁-Integrin). Blood 1994; 83: 1244-1250
• 15 Savage B, Shattil SJ, Ruggeri ZM. Modulation of platelet function through adhesion receptors: A dual role for glycoprotein IIb-IIIa (integrin α_IIbβ₃) mediated by fibrinogen and glycoprotein Ib-von Willebrand factor. J Biol Chem 1992; 267: 11300-11306
• 16 Savage B, Bottini E, Ruggeri ZM. Interaction of integrin α_IIbβ₃ with multiple fibrinogen domains during platelet adhesion. J Biol Chem 1995; 270: 28812-28817
• 17 Lefkovits J, Plow EF, Topol EJ. Platelet glycoprotein Ilb/IIIa receptors in cardiovascular medicine. N Engl J Med 1995; 332: 1553-1559
• 18 Howard MA, Firkin BG. Ristocetin —A new tool in the investigation of platelet aggregation. Thromb Haemost 1971; 26: 362-369
• 19 Read MS, Smith SV, Lamb MA, Brinkhous KM. Role of botrocetin in platelet agglutination formation of an activated complex of botrocetin and von Willebrand factor. Blood 1989; 74: 1031-1035
• 20 Kroll MH, Harris TS, Moake JL, Handin RI, Schafer AI. von Willebrand Factor binding to platelet GPIb initiates signals for platelet activation. J Clin Invest 1991; 88: 1568-1573
• 21 Chow TW, Heliums JD, Moake JL, Kroll MH. Shear stress-induced von Willebrand factor binding to platelet glycoprotein lb initiates calcium influx associated with aggregation. Blood 1992; 80: 113-120
• 22 Peterson DM, Stathopoulos NA, Giorgio TD, Heliums JD, Moake JL. Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins lb and Ilb-IIIa. Blood 1987; 69: 625-628
• 23 Ikeda Y, Handa M, Kawano K, Kamata T, Murata M, Araki Y, Anbo H, Kawai Y, Watanabe K, Itagaki I, Sakai K, Ruggeri ZM. The role of von Willebrand Factor and fibrinogen in platelet aggregation under varying shear stress. J Clin Invest 1991; 87: 1234-1240
• 24 De Marco L, Girolami A, Russell S, Ruggeri ZM. Interaction of asialo von Willebrand factor with glycoprotein lb induces fibrinogen binding to the glycoprotein Ilb/IIIa complex and mediates platelet aggregation. J Clin Invest 1985; 75: 1198-1203
• 25 De Marco L, Girolami A, Zimmerman TS, Ruggeri ZM. Interaction of purified IIB von Willebrand factor with the platelet membrane glycoprotein lb induces fibrinogen binding to the glycoprotein Ilb/IIIa complex and initiates aggregation. Proc Natl Acad Sci USA 1985; 82: 7424-7428