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Thromb Haemost 1985; 54(04): 901
DOI: 10.1055/s-0038-1660163
Letter to the Editor
Schattauer GmbH Stuttgart

Dihomo-γ-Linolenic Acid in Patients with Atherosclerosis: Effects on Platelet Aggregation, Plasma Lipids and Low-Density Lipoprotein-Induced Inhibition of Prostacyclin Generation

Authors

  • D P Mikhailidis

    Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK

  • M A Barradas

    Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK

  • P Dandona

    Department of Chemical Pathology and Human Metabolism, Royal Free Hospital and School of Medicine, London NW3 2QG, UK
Further Information

Publication History

Received 03 December 1984

Accepted 16 September 1985

Publication Date:
19 July 2018 (online)

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  • References

  • 1 Szczeklik A, Gryglewski RJ, Sladek K, Kostka-Trabka E, Zmuda A. Dihomo-y-linolenic acid in patients with atherosclerosis: effects on platelet aggregation, plasma lipids and low-density lipoprotein-induced inhibition of prostacyclin generation. Thromb Haemostas 1984; 51: 186-188
    PubMedSearch in Google Scholar
  • 2 Mikhailidis DP, Kirtland SJ, Barradas MA, Dandona P. Dihomogammalinolenic acid inhibits platelet aggregation and stimulates platelet prostaglandin production in healthy subjects: absence ofeffects in insulin-dependent diabetics. Diabetologia 1984; 27: 311A
    PubMedSearch in Google Scholar
  • 3 Hutton RA, Mikhailidis DP, Bernstein RM, Jeremy JY, Hughes GR V, Dandona P. Assessment of platelet functionin patients with Raynaud’s syndrome. J Clin Pathol 1983; 37: 182-187
    PubMedSearch in Google Scholar
  • 4 Mikhailidis DP, Mikhailidis AM, Barradas MA, Dandona P. Effect of nonesterified fatty acids on the stability of prostacyclin activity. Metabolism 1983; 32: 717-721
    CrossrefPubMedSearch in Google Scholar
  • 5 Brox JH, Nordoy A. The effect of polyunsaturated fatty acids on endothelial cells andtheir production of prostacyclin, thromboxane and platelet inhibitory activity. Thromb Haemostas 1983; 50: 762-767
    PubMedSearch in Google Scholar
  • 6 Dandona P, Lomeo F, Khokher MA, Houlder S. Dihomogammalinolenic acid (DHLA) and linolenic acid potentiate thestimulatory effect of insulin and adipocyte lipogenesis. Diabetes 1983; 32 (Suppl. 01) 60A
    PubMedSearch in Google Scholar