Thromb Haemost 1984; 51(02): 279-282
DOI: 10.1055/s-0038-1661077
Original Article
Schattauer GmbH Stuttgart

Acute Platelet Activation Induced by Smoking

In Vivo and Ex Vivo Studies in Humans
Kai Gjerløff Schmidt
The Department of Radiophysics, Odense University Hospital, Odense, Denmark
,
Jens Wæver Rasmussen
The Department of Radiophysics, Odense University Hospital, Odense, Denmark
› Author Affiliations
Further Information

Publication History

Received 08 November 1983

Accepted 30 December 1983

Publication Date:
19 July 2018 (online)

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Summary

Indices of acute in vivo platelet activation in response to cigarette smoking were sought in 10 healthy subjects. Judging by platelet aggregate ratio, platelet factor 4 and beta-thromboglobulin measurements, platelet activation took place from 10 to 30 min after smoking in most subjects. These signs correlated well with the results of scintigraphic studies showing signs of accumulation of 111-In-labelled platelets in the spleen in response to smoking.