FVIII, Protein C and the Risk of Arterial Thrombosis: More than the Sum of Its Parts

Thromb Haemost 2018; 118(07): 1127-1129
DOI: 10.1055/s-0038-1661373

Invited Editorial Focus

Georg Thieme Verlag KG Stuttgart · New York

Autor*innen

Bob Siegerink

¹Center for Stroke Research Berlin, Charité Universitätsmedizin Berlin, Berlin Germany

²Department of Clinical Epidemiology, Leiden University Medical Center, Leiden University, Leiden, the Netherlands

References
1 Zakai NA, Judd SE, Kissela B, Howard G, Safford MM, Cushman M. Factor VIII, Protein C and Cardiovascular Disease Risk: The REasons for Geographic and Racial Differences in Stroke Study (REGARDS). Thromb Haemost 2018; 118 (07) 1305-1315
2 Maino A, Rosendaal FR, Algra A, Peyvandi F, Siegerink B. Hypercoagulability is a stronger risk factor for ischaemic stroke than for myocardial infarction: A systematic review. PLoS One 2015; 10: e0133523
3 Ten Cate H, Hackeng TM, García de Frutos P. Coagulation factor and protease pathways in thrombosis and cardiovascular disease. Thromb Haemost 2017; 117 (07) 1265-1271
4 Siegerink B, Govers-Riemslag JWP, Rosendaal FR, Ten Cate H, Algra A. Intrinsic coagulation activation and the risk of arterial thrombosis in young women: results from the Risk of Arterial Thrombosis in relation to Oral contraceptives (RATIO) case-control study. Circulation 2010; 122 (18) 1854-1861
5 Vandenbroucke JP, von Elm E, Altman DG. , et al; STROBE initiative. Strengthening the Reporting of Observational Studies in Epidemiology (STROBE): explanation and elaboration. Ann Intern Med 2007; 147 (08) W163-W194
6 de Mutsert R, Jager KJ, Zoccali C, Dekker FW. The effect of joint exposures: examining the presence of interaction. Kidney Int 2009; 75 (07) 677-681
7 Li R, Chambless L. Test for additive interaction in proportional hazards models. Ann Epidemiol 2007; 17 (03) 227-236