Thorac cardiovasc Surg
DOI: 10.1055/s-0038-1667326
Original Cardiovascular
Georg Thieme Verlag KG Stuttgart · New York

Fibrin-Coated Collagen Fleece Seems to Prevent Sternal Instability after Cardiac Surgery: A Matched Pair Data Analysis

Peter Roth
1  Department of Adult and Pediatric Cardiovascular Surgery, Giessen University Hospital, Giessen, Germany
,
Jenna Stella
1  Department of Adult and Pediatric Cardiovascular Surgery, Giessen University Hospital, Giessen, Germany
,
Bernd Niemann
1  Department of Adult and Pediatric Cardiovascular Surgery, Giessen University Hospital, Giessen, Germany
,
Philippe Grieshaber
1  Department of Adult and Pediatric Cardiovascular Surgery, Giessen University Hospital, Giessen, Germany
,
Rainer Roehrig
2  Department of Medical Informatics, Carl von Ossietzky University Oldenburg, Oldenburg, Germany
,
Andreas Böning
1  Department of Adult and Pediatric Cardiovascular Surgery, Giessen University Hospital, Giessen, Germany
› Author Affiliations
Further Information

Publication History

04 March 2018

26 June 2018

Publication Date:
28 August 2018 (online)

Abstract

Background To examine if fibrin-coated collagen fleece (Tachosil) interferes with bone and wound healing when it is used on the cut surface of the sternum after median sternotomy.

Methods A total of 25 patients with osteoporotic sternal disorders were treated with fibrin-coated collagen fleece at the cut surface of the sternum after median sternotomy (therapy group). We compared the occurrence of impaired wound healing and sternal instability, reoperation rate, and 30-day mortality with a control group of 25 case-matched patients. After matching for age, gender, and risk factors for sternal instability (diabetes mellitus, osteoporosis, body mass index, nicotine consumption), both groups were comparable.

Results Sternal instability occurred in one (4%) patient in the study group and in five (20%) patients in the control group. Impaired wound healing occurred in one (4%) patient in the therapy group and two (8%) patients in the control group. Reoperation was necessary in four (16%) patients in the therapy group and 6 (24%) patients in the control group. The 30-day mortality occurred in six (24%) patients in the therapy group and four (16%) patients in the control group.

Conclusions The use of fibrin-coated collagen fleece on the cut surface of the sternum in patients with osteoporosis does not impair bone and wound healing. Furthermore, it seems to result in less sternal instability. A larger prospective study is necessary to verify the results of this explorative study.