CC BY 4.0 · TH Open 2018; 02(03): e261-e264
DOI: 10.1055/s-0038-1669456
Case Report
Georg Thieme Verlag KG Stuttgart · New York

Mesenteric Vein Thrombosis Following Platelet Transfusion in a Patient with Hemorrhagic Fever with Renal Syndrome: A Case Report

Anne-Marie Connolly-Andersen
1   Department of Clinical Microbiology, Infectious Diseases, Umeå University, Umeå, Sweden
,
Johan Rasmuson
1   Department of Clinical Microbiology, Infectious Diseases, Umeå University, Umeå, Sweden
,
Mikael Öman
2   Department of Surgical and Perioperative Sciences, Surgery, Umeå University, Umeå, Sweden
,
Clas Ahlm
1   Department of Clinical Microbiology, Infectious Diseases, Umeå University, Umeå, Sweden
› Author Affiliations
Funding This work was supported by The Swedish Society of Medicine (SLS-690711); Scandinavian Research Foundation for Varicose Veins and other Venous Diseases; Swedish Heart-Lung Foundation (20170334); The County Council of Västerbotten (VLL-579011; VLL-578991); The Medical Faculty, Umeå University (FS 2.1.12–1605–14); and the Swedish Foundation for Strategic Research (SB12–0003).
Further Information

Publication History

22 November 2017

23 July 2018

Publication Date:
27 August 2018 (online)

Introduction

Viral hemorrhagic fevers (VHFs) are typically characterized by life-threatening thrombocytopenia and tendency to bleed. Still, there are gaps of knowledge regarding risks and benefits of platelet transfusion for patients with severe thrombocytopenia during VHF and other infectious diseases.[1] [2] [3] [4] Hemorrhagic fever with renal syndrome (HFRS) is a mild rodent-borne VHF, caused by Puumala virus, endemic in central and northern Europe. The infection is characterized by fever, nausea, back- and headache, thrombocytopenia, and transient renal impairment. We have shown that HFRS is a risk factor for both arterial and venous thrombosis.[5] [6] We here report a case of a patient with HFRS with prolonged thrombocytopenia who developed thrombosis shortly after receiving platelet transfusion.