Geburtshilfe Frauenheilkd 2018; 78(10): 266
DOI: 10.1055/s-0038-1671569
Freitag, 02.11.2018
Case-Report VI
Georg Thieme Verlag KG Stuttgart · New York

Case report: Pregnancy in a 19-year-old mother with MODY 3 diabetes and father with MODY 2 diabetes complicated by dramatically falling insulin requirements

A Mikuscheva
1  Waikato Hospital, Gynäkologie Geburtshilfe, Hamilton, Neuseeland
› Author Affiliations
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Publication History

Publication Date:
20 September 2018 (online)


Maturity-Onset Diabetes of the young' (MODY) or monogenic diabetes accounts for approximately 1 – 2% of diabetes and is frequently misdiagnosed as type 1 or type 2 diabetes. Here we report a case of a 19-year-old pregnant woman with a MODY3 diabetes expecting a child to a father with MODY 2 diabetes and discuss the implications of the parent's mutations on the course of the pregnancy in detail. The pregnancy was complicated by drastically falling insulin requirements in the mother in the 3rd trimester as well as preterm labour and delivery at 33+4 weeks gestation. Genetic testing of the new-born showed a likely non-pathological variant of a HNF-1a mutation.