Abstract
Hepatobiliary malignancies during pregnancy are extremely rare and portend a poor
prognosis. There are only seven published cases of cholangiocarcinoma in an obstetrical
patient, all are cases of primary cholangiocarcinoma (1–7). Herein, we describe the
first case of recurrent cholangiocarcinoma during pregnancy. The patient did not receive
chemotherapy during pregnancy and required prolonged hospitalizations for nutritional
and intensive medical support. She delivered preterm, at 30 2/7 weeks gestation, after developing pre-eclampsia with severe features. The infant
was healthy, with no malformations, and currently exhibits no neurological or behavioral
sequelae at 8months of age. We discuss themanagement considerations inherent to this
complex clinical scenario including metastatic disease severity, ethical considerations,
and palliative care treatment options.
Keywords
cancer - pregnancy - cholangiocarcinoma - hepatobiliary
