Int J Angiol 2019; 28(01): 050-056
DOI: 10.1055/s-0038-1676791
Original Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Diabetics have Inferior Long-Term Survival and Quality of Life after CABG

Otso Järvinen
1  Department of Cardiothoracic Surgery, Heart Center, Tampere University Hospital, Tampere, Finland
,
Matti Hokkanen
2  Department of Surgery, Jyväskylä Central Hospital, Jyväskylä, Finland
,
Heini Huhtala
3  Faculty of Social Sciences, University of Tampere, Tampere, Finland
› Author Affiliations
Further Information

Publication History

Publication Date:
02 January 2019 (eFirst)

Abstract

A prevalence of diabetes is increasing among the patients undergoing coronary artery bypass grafting (CABG). Data on whether health-related quality of life improves similarly after CABG in diabetics and nondiabetics are limited. We assessed long-term mortality and changes in quality of life (RAND-36 Health Survey) after CABG.

Seventy-four of the 508 patients (14.6%) operated on in a single institution had a history of diabetes and were compared with nondiabetics. The RAND-36 Health Survey was used as an indicator of quality of life. Assessments were made preoperatively and repeated 1 and 12 years later.

Thirty-day mortality was 2.7 versus 1.6 (p = 0.511) in the diabetics and nondiabetics. One- and 10-year survival rates in the diabetics and nondiabetics were 94.6% versus 97.0% (p = 0.287) and 63.5% versus 81.6% (p < 0.001), respectively. After 1 year, diabetics improved significantly (p < 0.005) in seven, and nondiabetics (p < 0.001) in all eight RAND-36 dimensions. Despite an ongoing decline in quality of life over the 12-year follow-up, an improvement was maintained in four out of eight dimensions among diabetics and in seven dimensions among nondiabetics. Physical and mental component summary scores on the RAND-36 improved significantly (p < 0.001) in both groups after 1 year, and at least slight improvement was maintained during the 12-year follow-up time.

Diabetics have inferior long-term survival after CABG as compared with nondiabetics. They gain similar improvement of quality of life in 1 year after surgery, but they have a stronger decline tendency over the years.