Intermittent Antegrade Warm Blood Cardioplegia: What Is Next?Funding None.
21 December 2018
22 January 2019
05 March 2019 (online)
The introduction of warm heart surgery was a radical change in the concept of myocardial protection. In 1992, we applied a protocol for intermittent antegrade warm blood cardioplegia (CPL), which acquired some popularity for its simplicity and effectiveness. The possibility to deliver the warm blood CPL intermittently using the antegrade route attracted the attention of the scientific world, as the surgical procedure was less complicated. In this report, our aim is to focus on the changes that the protocol underwent over time and the reasons why these changes were made.
None to disclose.
- 1 Salerno TA, Houck JP, Barrozo CA. , et al. Retrograde continuous warm blood cardioplegia: a new concept in myocardial protection. Ann Thorac Surg 1991; 51 (02) 245-247
- 2 Lichtenstein SV, Ashe KA, el Dalati H, Cusimano RJ, Panos A, Slutsky AS. Warm heart surgery. J Thorac Cardiovasc Surg 1991; 101 (02) 269-274
- 3 Calafiore AM, Teodori G, Mezzetti A. , et al. Intermittent antegrade warm blood cardioplegia. Ann Thorac Surg 1995; 59 (02) 398-402
- 4 Mezzetti A, Calafiore AM, Lapenna D. , et al. Intermittent antegrade warm cardioplegia reduces oxidative stress and improves metabolism of the ischemic-reperfused human myocardium. J Thorac Cardiovasc Surg 1995; 109 (04) 787-795
- 5 Tian G, Xiang B, Butler KW. , et al. A 31P-nuclear magnetic resonance study of intermittent warm blood cardioplegia. J Thorac Cardiovasc Surg 1995; 109 (06) 1155-1163
- 6 Franke UF, Korsch S, Wittwer T. , et al. Intermittent antegrade warm myocardial protection compared to intermittent cold blood cardioplegia in elective coronary surgery--do we have to change?. Eur J Cardiothorac Surg 2003; 23 (03) 341-346
- 7 Mallidi HR, Sever J, Tamariz M. , et al. The short-term and long-term effects of warm or tepid cardioplegia. J Thorac Cardiovasc Surg 2003; 125 (03) 711-720
- 8 Hirose M, Hirose Y, Gamou M, Harigae M, Fujiwara C. The efficiency of intermittent antegrade warm blood cardioplegia [in Japanese]. Masui 1999; 48 (01) 48-52
- 9 Caputo M, Bryan AJ, Calafiore AM, Suleiman MS, Angelini GD. Intermittent antegrade hyperkalaemic warm blood cardioplegia supplemented with magnesium prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery. Eur J Cardiothorac Surg 1998; 14 (06) 596-601
- 10 Flameng WJ, Herijgers P, Dewilde S, Lesaffre E. Continuous retrograde blood cardioplegia is associated with lower hospital mortality after heart valve surgery. J Thorac Cardiovasc Surg 2003; 125 (01) 121-125
- 11 Ardehali A, Laks H, Drinkwater Jr DC, Gates RN, Kaczer E. Ventricular effluent of retrograde cardioplegia in human hearts has traversed capillary beds. Ann Thorac Surg 1995; 60 (01) 78-82 , discussion 82–83
- 12 Ruengsakulrach P, Buxton BF. Anatomic and hemodynamic considerations influencing the efficiency of retrograde cardioplegia. Ann Thorac Surg 2001; 71 (04) 1389-1395
- 13 Kouerinis IA, Manopoulos CG, Zografos GC. , et al. Retrograde cardioplegia in CABG: is it really useful? The microcirculation and a capillary unit model. Med Sci Monit 2006; 12 (11) RA265-RA268
- 14 Ghazy T, Allham O, Ouda A, Kappert U, Matschke K. Is repeated administration of blood-cardioplegia really necessary?. Interact Cardiovasc Thorac Surg 2009; 8 (05) 517-521
- 15 Hoyer A, Lehmann S, Mende M. , et al. Custodiol versus cold Calafiore for elective cardiac arrest in isolated aortic valve replacement: a propensity-matched analysis of 7263 patients. Eur J Cardiothorac Surg 2017; 52 (02) 303-309
- 16 Kuhn EW, Liakopoulos O, Slottosch I. , et al. Buckberg versus Calafiore cardioplegia in patients with acute coronary syndromes. Thorac Cardiovasc Surg 2018; 66 (06) 457-463
- 17 Zeriouh M, Heider A, Rahmanian PB. , et al. Six-years survival and predictors of mortality after CABG using cold vs. warm blood cardioplegia in elective and emergent settings. J Cardiothorac Surg 2015; 10: 180
- 18 Sobieraj M, Kilanowska M, Ładziński P. , et al. Type of cardioplegic solution as a factor influencing the clinical outcome of open-heart congenital procedures. Kardiochir Torakochirurgia Pol 2018; 15 (02) 86-94