Synkinetic reinnervation in ini- and bilateral recurrent laryngeal nerve paralyses

Meanwhile it could be shown in animal studies that the synkinetic reinnervation in uni- or bilateral recurrent nerve paralysis (UVFP, BFVP) is more the rule than the exception, although clinically special emphasis is given to the perspective of either temporary or permanent paralysis. Synkinetic reinnervation might give more detailed explanation of uncommon clinical symptoms in patients with either UVFP or BVFP.

Goal of the study was the retrospective analysis of laryngeal EMG examination between 2015 and 2018. LEMG data of 103 patients (47 male, 56 female) could be included. In 21 of 84 patients with UFVP and in 13 of the 19 patients with BFVP signs for synkinetic reinnervation could be found. The statistical analyses revealed a synkinetic reinnervation in UVFP after at least 2 months or even longer (p = 0,022). For the statistical analysis of duration BFVP and occurrence of synkinetic reinnervation the test population was too small.

LEMG is the gold standard for diagnosing a synkinetic reinnervation in UVFP and BVFP. It should be performed earliest after 2 months after begin of the paresis. The knowledge of synkinetic reinnervation is essential for therapeutic option for instance regarding the application of Botulinum toxin and in future the laryngeal pacemaker.

Publication History

Publication Date:
23 April 2019 (online)