NBI-Role in early diagnosis of upper aerodigestive tract malignancy

Introduction:

Narrow Band Imaging (NBI) is an optical image enhancement technology that improves the visibility of vessels and other tissues on mucosal surface. It uses filtered wavelengths to enhance microvascular abnormalities associated with the preneoplastic and neoplastic changes of the mucosal lining of the upper aerodigestive tract. These abnormal vascular patterns have been recently demonstrated to be useful tool in diagnosis of upper aerodigestive tract pathology.

Aim:

The purpose of this study was to assess the efficacy of NBI as a diagnostic tool in early detection of upper aerodigestive tract cancer and precancerous lesion.

Methods and methodology:

This study is a prospective study conducted on 100 patients with upper aerodigestive tract lesions planned for examination under general anesthesia and biopsy. All patients underwent white light endoscopy, Narrow band imaging and then a biopsy for histopathological diagnosis. NBI images were classified into 5 types based on the intrapaillary capillary loop patterns. Type V(a/b/c) lesions was considered malignant. NBI findings were correlated with HPR.

Conclusion:

The results of this study demonstrates NBI as an excellent technique for early detection of upper aerodigestive tract malignancy with significantly higher sensitivity than White light endoscopy alone.

Publication History

Publication Date:
23 April 2019 (online)