Comprehensive treatment of 31 pafients with hypopharyngeal carcinoma by surgery via the paraglottic space approach

Introduction:

Hypopharyngeal carcinoma is one of the most malignant tumors in the head and neck. The principle of treatment should be to minimize the damage of organ function on the premise of maximizing the local control because of the important function will involve pronunciation, swallowing, respiration. The improvement of surgical technique can not only increase the probability of radical resection, but also improve the preservation rate of laryngeal function. We retrospectively analyzed and summarized the therapeutic effect the clinical data of hypopharyngeal cancer patients treated by paraglottic space approach. Methods 31 cases without distant metastasis (according to UICC 2012, stage I, 2; II, 3; IlI, 6; IV, 20) treated between 2009.01 to 2013.12 were retrospectively reviewed.27 cases were treated with pharyngeal residual mucosa suture and 4 cases with pectoralis major myocutaneous flap. All patients underwent neck dissection. Preoperative induction chemotherapy was performed in 5 cases, preoperative neoadjuvant radiotherapy and chemotherapy in 3 cases, post-operative radiotherapy in all cases, and concurrent radiotherapy and chemotherapy in 5 cases.

Results:

The laryngeal function was preserved in 25 cases. Postoperative pathology confirmed lymph node metastasis in 24 cases.2 cases of pharyngeal fistula occurred after operation, including 1 cases during radiotherapy. All patients were well fed before discharge and gastric tube was removed. The follow-up rate was 96.8%, the overall 3 and 5 year survival rates were 64.5%and 51.6%

Conclusions:

Paraglottic space approach is effective for hypopharyngeal cancer resection. This method can effectively preserve laryngeal function.

Publication History

Publication Date:
23 April 2019 (online)