CC BY-NC-ND 4.0 · Laryngorhinootologie 2019; 98(S 02): S310
DOI: 10.1055/s-0039-1686358

Objective assessment of vertigo causing perilymphatic fistula in cochlear implantees by cochlin-tomoprotein (CTP)

A Darwish
1   Klinikum Bielefeld, Bielefeld
H Sudhoff
1   Klinikum Bielefeld, Bielefeld
I Todt
1   Klinikum Bielefeld, Bielefeld
› Author Affiliations


A well-known and frequently reported complication after cochlear implantation is the appearance of postoperative vertigo symptoms. Perilymphatic fistula (PLF) is a known cause for hearing loss and vertigo. Cochlin-tomoprotein (CTP) is a cochlear specific protein acting as a marker for PLF. Aim of the present study was to observe, if the postoperatively new occurence of vertigo is caused by a perilymphatic fistula evidenced by CTP marker.


In a prospective analysis 12 cochlear implant patients with the postoperatively new occurence ofvertigo underwent a transtympanallyrevison/resealing surgery. In all patients middle ear fluid was captured and analysed for CTP.


In 5 out of 12 patients a positive CTP result was found indicating a PLF. Positive PLF finding did not correlate with the intraoperative visual assumption of a leak. The procedure solves in most of the cases the vertigo problem.


Our present finding demonstrates that objectively an insufficent sealing causing perilymphatic fistula occurs in cases of newly postoperative vertigo after cochlea implantation.

Publication History

Publication Date:
23 April 2019 (online)

© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (

Georg Thieme Verlag KG
Stuttgart · New York