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DOI: 10.1055/s-0039-1686860
Case-report of a huerthle cell adenoma in an 11-year-old girl
Introduction:
Thyroid nodules occur very rarely in children (1 – 2% of this population). However, they are more often malignant compared to adults (mean 26,4%). Only a very small percentage of thyroid nodules in children can be classified as huerthle cell tumors ( < 5%). Huerthle cells (frequently employed synonyme: „oncocytes“) are follicular-derived epithelial cells with an acidophilic cytoplasma containing a vast number of mitochondria. There exist both benign and malignant hurthle cell tumors.
Results:
We report on an 11-year-old girl with a 4 cm measuring nodule of the thyroid isthmus. The nodule could be classified as a huerthle cell adenoma. During our MEDLINE research we found only 3 case-reports of huerthle cell adenomas in minors.
Conclusions:
Studying present literature we describe a rare differential diagnosis of pediatric thyroid nodule. In this context we would like to discuss new diagnostic technology such as molecular testing with fine needle aspiration biopsy.
Publication History
Publication Date:
23 April 2019 (online)
© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Stuttgart · New York