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DOI: 10.1055/s-0039-1686860
Case-report of a huerthle cell adenoma in an 11-year-old girl
Introduction:
Thyroid nodules occur very rarely in children (1 – 2% of this population). However, they are more often malignant compared to adults (mean 26,4%). Only a very small percentage of thyroid nodules in children can be classified as huerthle cell tumors ( < 5%). Huerthle cells (frequently employed synonyme: „oncocytes“) are follicular-derived epithelial cells with an acidophilic cytoplasma containing a vast number of mitochondria. There exist both benign and malignant hurthle cell tumors.
Results:
We report on an 11-year-old girl with a 4 cm measuring nodule of the thyroid isthmus. The nodule could be classified as a huerthle cell adenoma. During our MEDLINE research we found only 3 case-reports of huerthle cell adenomas in minors.
Conclusions:
Studying present literature we describe a rare differential diagnosis of pediatric thyroid nodule. In this context we would like to discuss new diagnostic technology such as molecular testing with fine needle aspiration biopsy.
Publikationsverlauf
Publikationsdatum:
23. April 2019 (online)
© 2019. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Georg Thieme Verlag KG
Stuttgart · New York