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CC BY-NC-ND 4.0 · Eur J Dent 2019; 13(03): 303-309
DOI: 10.1055/s-0039-1688738
Original Article
Dental Investigation Society

Correlation of Radiomorphometric Indices of the Mandible and Biochemical Parameters in Patients with Secondary Hyperparathyroidism Due to Chronic Kidney Disease

Stenio Medeiros Queiroz
1   Department of Dentistry, Health Sciences Postgraduate Program, Federal University of Rio Grande Do Norte, Natal, Rio Grande do Norte, Brazil
,
Ana Luiza Dias Leite De Andrade
2   Department of Dentistry, Oral Pathology Postgraduate Program, Federal University of Rio Grande Do Norte, Natal, Rio Grande do Norte, Brazil
,
Patrícia Teixeira De Oliveira
3   Department of Dentistry, Postgraduate Program in Dental Sciences, Federal University of Rio Grande do Norte, Natal, Brazil
,
Paulo Raphael Leite Maia
3   Department of Dentistry, Postgraduate Program in Dental Sciences, Federal University of Rio Grande do Norte, Natal, Brazil
,
Ângelo Giuseppe Roncalli Da Costa Oliveira
3   Department of Dentistry, Postgraduate Program in Dental Sciences, Federal University of Rio Grande do Norte, Natal, Brazil
,
Roseana De Almeida Freitas
2   Department of Dentistry, Oral Pathology Postgraduate Program, Federal University of Rio Grande Do Norte, Natal, Rio Grande do Norte, Brazil
,
Hébel Cavalcanti Galvão
1   Department of Dentistry, Health Sciences Postgraduate Program, Federal University of Rio Grande Do Norte, Natal, Rio Grande do Norte, Brazil
› Author Affiliations Funding The authors thank the Foundation for Research Support of the State of Rio Grande do Norte, Brazil, for financial support, and all the hemodialysis centers that contributed to the study.
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Publication History

Publication Date:
03 December 2019 (online)

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Abstract

Objective The aim was to correlate radiomorphometric indices and biochemical analyses as an auxiliary method in bone evaluation in male and female patients with chronic kidney disease–mineral and bone disorder (CKD-MBD) and controls.

Materials and Methods Nine radiomorphometric indices and four biochemical parameters were obtained: mental index (MI), height at the mental foramen, total mandibular height (THM), panoramic mandibular index (PMI), original height of the mandible, alveolar bone resorption, distance from the mental foramen to the alveolar bone crest (MF-ABC), mandibular cortical index (MCI), trabecular bone pattern, parathyroid hormone (PTH), calcium (Ca), phosphorus (P), and Ca × P product (Ca × P).Statistical Analysis The Mann–Whitney U-test, chi-squared test, and Spearman’s correlation were applied at a significance level of 95%.

Results There was a moderate negative and significant correlation between MI, PMI, and PTH in female patients with CKD-MBD as well as between THM, MF-ABC, and Ca × P. The MCI and trabecular bone pattern indicated altered bone quality in male patients.

Conclusions The radiomorphometric evaluation was an auxiliary, noninvasive method to detect possible alterations in the cortex and mandibular bone trabeculation in male and female patients with CKD-MBD.

Keywords

chronic kidney disease - panoramic radiography - radiomorphometric indices - renal osteodystrophy - secondary hyperparathyroidism
 

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