Int J Angiol 2019; 28(04): 215-225
DOI: 10.1055/s-0039-1692448
Review Article
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Current Controversies in Large-Vessel Inflammatory Vasculitis and Thoracic Aortic Aneurysm Disease

Amer Harky
1   Department of Vascular Surgery, Countess of Chester Hospital, Chester, United Kingdom
,
Matthew Fok
2   Department of General Surgery, Royal Liverpool Hospital, Liverpool, United Kingdom
,
Callum Howard
3   Department of Aortovascular Surgery, Manchester Royal Infirmary, Manchester, United Kingdom
,
Mohamad Bashir
3   Department of Aortovascular Surgery, Manchester Royal Infirmary, Manchester, United Kingdom
› Author Affiliations
Further Information

Publication History

Publication Date:
28 June 2019 (online)

Abstract

Large-vessel vasculitis encompasses the spectrum of vasculitides, which pathologically cause chronic granulomatous inflammatory changes, primarily in the aorta and its major branches. These patients are at risk of developing life-threatening aortic lesions that, without recognition and prompt treatment, can cause detrimental effects. Many provocative issues surrounding large-vessel vasculitis and its surgical treatment still remain, spanning from recognition to management. In this review, we discuss the main large-vessel vasculitides, Takayasu's arteritis and giant cell arteritis. We include the key points and current controversies surrounding diagnostic imaging, timing of interventions, and patient outcomes.

Disclosures

None.


 
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