J Neurol Surg B Skull Base 2020; 81(05): 511-514
DOI: 10.1055/s-0039-1692640
Original Article

MRI and CT Guided Cryoablation for Intracranial Extension of Malignancies along the Trigeminal Nerve

Thomas C. Lee
1  Division of Neuroradiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Jeffrey P. Guenette
1  Division of Neuroradiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Ziev B. Moses
2  Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Jong Woo Lee
3  Department of Neurology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
Donald J. Annino
4  Division of Otolaryngology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
,
John H. Chi
2  Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, United States
› Author Affiliations

Abstract

Objectives To describe the technical aspects and early clinical outcomes of patients undergoing percutaneous magnetic resonance imaging (MRI)-guided tumor cryoablation along the intracranial trigeminal nerve.

Design This study is a retrospective case review.

Setting Large academic tertiary care hospital.

Participants Patients who underwent MRI-guided cryoablation of perineural tumor along the intracranial trigeminal nerve.

Main Outcome Measures Technical success, pain relief, local control.

Results Percutaneous MRI-guided cryoablation of tumor spread along the intracranial portion of the trigeminal nerve was performed in two patients without complication, with subsequent pain relief, and with local control in the patient with follow-up imaging.

Conclusions Percutaneous MRI-guided cryoablation is a feasible treatment option for malignancies tracking intracranially along the trigeminal nerve.

Grants, Disclosures, and Other Assistance

The Advanced Multimodality Image Guided Operating Suite was supported in part by the National Institutes of Health (grant P41 EB 015898).


Institutional Review Board Statement

The study was approved by our institutional review board.




Publication History

Received: 14 February 2019

Accepted: 05 May 2019

Publication Date:
12 June 2019 (online)

Georg Thieme Verlag KG
Stuttgart · New York