Open Access
CC BY-NC-ND 4.0 · J Neuroanaesth Crit Care 2019; 06(02): 145-152
DOI: 10.1055/s-0039-1692868
Review Article
Indian Society of Neuroanaesthesiology and Critical Care

Pharmacologic Treatment of Meningitis and Encephalitis in Adult Patients

Andrew K. Treister
1   Department of Neurology, Oregon Health & Science University, Portland, Oregon, United States
,
Ines P. Koerner
2   Department of Anesthesiology and Perioperative Medicine, Oregon Health & Science University, Portland, Oregon, United States
› Author Affiliations
Further Information

Publication History

Received: 05 February 2019

Accepted after revision: 19 May 2019

Publication Date:
19 June 2019 (online)

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Abstract

Meningitis and encephalitis are two inflammatory, often infectious, disorders of the meninges and the central nervous system. Both are associated with significant morbidity and mortality, and require early and aggressive targeted treatment. This article reviews pharmacologic treatment strategies for infectious meningitis and encephalitis, using the latest available research and guidelines. It provides an overview of empiric antimicrobial treatment approaches for a variety of organisms, including a discussion of trends in antibiotic resistance where applicable. Key steps in diagnosis and general management are briefly reviewed.