Fulminant hepatic failure as initial presentation due to diffuse parenchymal infiltration
by cholangiocarcinoma is a rare entity. We present the case of a 49-year-old female
patient who had a fatal outcome with acute liver failure due to diffuse intrahepatic
cholangiocarcinoma. No definite mass lesion was identified on cross-sectional imaging.
The final diagnosis was made on transjugular liver biopsy. This discussion highlights
the possibility of infiltrative cholangiocarcinoma as a rare cause of fulminant hepatic
failure.
Keywords
fulminant hepatic failure - intrahepatic cholangiocarcinoma - transjugular liver biopsy