Abstract
Cryoneurolysis is the deliberate application of cold temperatures to nerves for therapeutic
purposes. The idea of treating pain with this technique is thousands of years old
and has evolved over time through the application of surgical techniques, nerve stimulation
and/or landmark guidance, and through device development. Recent integration of the
interventional radiology skill set to this space has unlocked a myriad of opportunities—primarily
through a unique ability to percutaneously access deep structures in the body with
accuracy and precision, and the capacity to monitor ablation zones. Understanding
of the specific neurohistological process that follows targeted cryoneurolysis leads
to new options for treating patients in pain without drugs and opens doors for the
potential modification of a wide array of disease states.
Keywords
interventional - cryoneurolysis - cryoanalgesia - cryoablation