Open Access
CC BY-NC-ND 4.0 · Eur J Dent 2009; 03(02): 96-99
DOI: 10.1055/s-0039-1697414
Original Article
Dental Investigation Society

Wound Healing Effects of Arnebia Densiflora Root Extracts on Rat Palatal Mucosa

H. Huseyin Kosger
a   Assistant Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Cumhuriyet University, Sivas, Turkey
,
Mustafa Ozturk
b   Associate Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gazi University, Ankara, Turkey
,
Atalay Sokmen
c   Professor, Department of Biology, Faculty of Science and Literature, Karadeniz Technical University, Trabzon, Turkey
,
Eray Bulut
d   Professor, Department of Histology and Embryology, Faculty of Medicine, Cumhuriyet University, Sivas, Turkey
,
Sinan Ay
e   Associate Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Gaziantep University, Gaziantep, Turkey
› Author Affiliations
Further Information

Publication History

Publication Date:
27 September 2019 (online)

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ABSTRACT

Objectives: The aim of this study was to investigate wound healing effects of Arnebia densiflora (Nordm.) Ledeb. root extracts on rat palatal mucosa.

Methods: A 10-mm full-thickness mucosal wounds were created on midline of rats’ palate by using scalpel. Inthe experimental groups, a ten percent extract of A. densiflora roots was topically applied once a day as ointment on the wounds. After wounding, tissue samples from palatal mucosa were harvested at 4, 7, 14 and 21 days and then evaluated histologically.

Results: It was observed that 10% A. densiflora root extract has progressive effects on wound healing in experimental groups.

Conclusions: This study suggests that A. densiflora root extract could be developed as a therapeutic agent for wound healing. (Eur J Dent 2009;3:96-99)