Download PDF
CC BY-NC-ND 4.0 · Indian Journal of Neurosurgery 2020; 9(02): 127-130
DOI: 10.1055/s-0039-3402622
Short Communication

A Distinct Scenario of a Patient with Parkinson’s Disease and Comorbid Normal Pressure Hydrocephalus

Halil Onder
1   Department of Neurology, Neurology Clinic, Yozgat City Hospital, Yozgat, Turkey
› Author Affiliations Funding None.
› Further Information
   Permissions and Reprints

Abstract

In literature, patients with coexistence of normal pressure hydrocephalus (NPH) and Parkinsons’s disease (PD) have been rarely reported. Herein, I illustrate the evaluation processes of a remarkable patient with PD and comorbid NPH from my experience, which I think may provide crucial perspectives regarding the management problems of these patients. Besides, the patient had also developed bipolar disorder in the follow-up course and extrapyramidal side effects related to antipsychotic medications, which further complicated the treatment process. I think that results of future reports of larger case series including the long-term follow-up of this group of patients with coexisting NPH and PD would provide substantial perspectives regarding the contributory effects of these two pathophysiologies, as well as management, of NPH in these specific patients with neurodegenerative pathology.

Keywords

Parkinson’s disease - normal pressure hydrocephalus - neurodegeneration - pathophysiology - treatment - shunt


Publication History

Article published online:
18 May 2020

© .

Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India

 

  • References

  • 1 Molde K, Söderström L, Laurell K. Parkinsonian symptoms in normal pressure hydrocephalus: a population-based study. J Neurol 2017; 264 (10) 2141-2148
    CrossrefPubMedGoogle Scholar
  • 2 Espay AJ, Da Prat GA, Dwivedi AK. et al. Deconstructing normal pressure hydrocephalus: Ventriculomegaly as early sign of neurodegeneration. Ann Neurol 2017; 82 (04) 503-513
    CrossrefPubMedGoogle Scholar
  • 3 Lee JY, Im K, Kwon KY. Parkinsonian patient with comorbid normal pressure hydrocephalus: clinical usefulness of diagnosis supported by neurological findings. Clin Neuroradiol 2018; 28 (04) 617-618
    CrossrefPubMedGoogle Scholar
  • 4 Cucca A, Biagioni MC, Sharma K. et al. Comorbid normal pressure hydrocephalus with Parkinsonism: a clinical challenge and call for awareness. Case Rep Neurol Med 2018; 2018: 2513474
    PubMedGoogle Scholar
  • 5 Nikaido Y, Akisue T, Kajimoto Y. et al. Postural instability differences between idiopathic normal pressure hydrocephalus and Parkinson’s disease. Clin Neurol Neurosurg 2018; 165: 103-107
    CrossrefPubMedGoogle Scholar