CC BY-NC-ND 4.0 · Laryngorhinootologie 2020; 99(S 02): S47
DOI: 10.1055/s-0040-1710846
Abstracts
Imaging/Sonography

The DOTATOC PET-CT as a potential new method for diagnostic imaging of pleomorphic adenomas

F Johnson
1   Klinikum rechts der Isar, Technische Universität München, Hals-, Nase, und Ohrenheilkunde München
,
B Feuerecker
2   Klinikum rechts der Isar, Technische Universität München, Diagnostische und Interventionelle Neuroradiologie München
,
L Lindner
1   Klinikum rechts der Isar, Technische Universität München, Hals-, Nase, und Ohrenheilkunde München
,
U Straßen
1   Klinikum rechts der Isar, Technische Universität München, Hals-, Nase, und Ohrenheilkunde München
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Introduction The surgical resection of pleomorphic adenomas is recommended due to the risk of malignant transformation. Current preoperative diagnostic imaging to determine the dignity of a suspected pleomorphic adenoma is non-specific. Recent studies have described the expression of somatostatin in pleomorphic adenomas. Goal of this study is to determine if the DOTATOC PET-CT may be used to identify pleomorphic adenomas.

Methods inclusion parameters for this monocentric retrospective observational study were all patients who received a DOTATOC PET-CT between 01.01.2010 and 12.31.2018 and who also received a saliva gland tumor resection (n = 14). Image assessment was performed through qualitative and semiquantitative analysis.

Results Of the 14 identified patients 5 patients had histologically confirmed pleomorphic adenomas. DOTATOC tracer-uptake was found to be increased in 80 % of these cases. The smallest PA (1,5ml) tumor showed no tracer-uptake. By 3 patients could histologically be diagnosed a Warthin-tumor, additionally an oncocytoma, lymphoma, a squamous cell carcinoma lymphnode metastasis, a granuloma, and chronical parotitis. No other tumors showed a relevant tracer-uptake. The average PA tumor volume was 13,3 ml (with a range of 1,5ml-55ml).

Conclusions This unknown diagnostic property with Tracer-Uptake in pleomorphic adenomas should be further researched, and could be utilized to preoperatively identify pleomorphic adenomas.

Poster-PDF A-1764.PDF



Publication History

Article published online:
10 June 2020

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