Homœopathic Links 2021; 34(03): 182-190
DOI: 10.1055/s-0040-1713875
Original Article

Effects of Blatta orientalis on Treatment of Bronchial Asthma: A Prospective, Non-Randomised, Open-Label, Observational Study

Hanuman Ram
1   Epidemic Cell, Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India
,
Prasoon Choudhary
2   Anatomy Department, Dr. MPK Homoeopathic Medical College, Hospital & Research Centre, Jaipur, Rajasthan, India
,
Deepti Dewan
3   Former Consultant, Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India
,
Arvind Kumar
4   Statistical Assistant, Central Council for Research in Homoeopathy, Ministry of AYUSH, Govt. of India, New Delhi, India
› Institutsangaben

Abstract

Background Bronchial asthma is a globally significant non-communicable disease with major public health consequences for both children and adults, including high morbidity, and relatively low mortality compared with other chronic diseases. It is a chronic disorder that compels the patient to take lifelong medications including bronchodilators.

Aim This study was undertaken to ascertain the effects of Blatta orientalis in centesimal potency on the treatment of bronchial asthma assessed by spirometry and Asthma Control Questionnaire (ACQ) Score.

Method A prospective, non-randomised, open-label, observational study was conducted at Dr. MPK Homoeopathic Medical College, Hospital & Research Centre, Jaipur, Rajasthan, from 2015 to 2016. Patients between 5 and 80 years of age suffering from dyspnoea, cough with expectoration and wheezing were screened. The convenience sampling technique was used to enrol 120 patients, after fulfilling the inclusion and exclusion criteria of the study. The patients of Bronchial asthma were treated with potentized Blatta orientalis for 6 months. Patients were diagnosed and assessed on the basis of the ACQ Score by Elizabeth Junipers and spirometry findings. Blatta orientalis was prescribed to all patients in increasing potency from 30C. The paired t-test was applied to calculate the statistical significance of the study.

Result Out of 120 patients, 100 had completed the study with follow-up of 6 months. A significant difference was found in pre- and post-treatment spirometry—that is, forced expiratory volume in 1 second/forced vital capacity (FEV1/FVC) ratio—from baseline to 6 months (mean ± standard deviation [SD]: –10.27 ± 4.95; 95% confidence interval [CI]: –11.25 to –9.28; p = 0.00001). Also, significant difference was seen in the ACQ Score from baseline to 6 months (mean ± SD: 19.44 ± 8.69; 95% CI: 17.71–21.16; p = 0.00001).

Conclusion The study findings are encouraging enough to prescribe Blatta orientalis in potency in cases of bronchial asthma. Further systematic replication is required. Conducted as randomised controlled trials with long-term follow-ups for definite conclusions.

Note

The trial protocol and full dissertation was submitted as a post-graduate thesis of the corresponding author.




Publikationsverlauf

Publikationsdatum:
21. Oktober 2020 (online)

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