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CC BY-NC-ND 4.0 · J Neurosci Rural Pract 2020; 11(04): 643-645
DOI: 10.1055/s-0040-1714329
Case Report

Effect of Cannabinoids on Electroencephalography of a Child with Lennox–Gastaut Syndrome

Vikram Prakash 
1   Department of Pediatric Neurology, Leon Pediatric Neuroscience Center of Excellence, Arnold Palmer Hospital, Orlando Health, Orlando, Florida, United States
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Abstract

Cannabinoids have been found to be effective in controlling seizures and the highly purified form of cannabinoid derived for Cannabis sativa. Cannabidiol (CBD) is now approved for Lennox–Gastaut syndrome (LGS) and Dravet syndrome. CBD was used in a 9-year-old boy with LGS (unknown etiology) with very good results. The electroencephalography (EEG) response was very dramatic with near normalization of EEG background and complete control of seizures. The effect of CBD on EEG with such an improvement has not been described previously. Also, this adds to evidence that early intervention in LGS with CBD might be more helpful and improve outcomes.

Keywords

cannabinoid - EEG - Lennox-Gastaut syndrome


Publication History

Article published online:
11 August 2020

© 2020. Association for Helping Neurosurgical Sick People. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. https://creativecommons.org/licenses/by-nc-nd/4.0/.

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